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Question

Vitamin B$_{12}$ deficiency can cause the following except:

The correct answer is
Myopathy

Vitamin B12 Deficiency: Identifying the Exception

Vitamin B12 deficiency primarily affects the nervous system and hematopoiesis. Understanding the common manifestations is key to identifying conditions that are exceptions.

Common Neurological and Ocular Effects of B12 Deficiency

Vitamin B12 is crucial for myelin sheath maintenance in the nervous system. Deficiency can lead to:

  • Myelopathy: Often presenting as subacute combined degeneration of the spinal cord.
  • Peripheral neuropathy: Affecting nerves outside the brain and spinal cord.
  • Optic atrophy: Damage to the optic nerve, potentially leading to vision loss.

Distinguishing Myopathy from Neurological Symptoms

Myopathy refers to a disease of the muscle itself. While severe neurological conditions caused by B12 deficiency (like extensive neuropathy) might indirectly lead to muscle weakness or secondary changes, myopathy is not typically listed as a direct or primary neurological or ophthalmological consequence of the deficiency itself. The other conditions listed (myelopathy, optic atrophy, peripheral neuropathy) are well-established neurological or related complications.

Therefore, myopathy is the condition listed that is least directly associated with Vitamin B12 deficiency.

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Important Questions from Vitamin B Complex Deficiency

  1. All of the following cause dementia EXCEPT:
  2. Which of the following is/are neurological manifestation(s) of vitamin $B_{12}$ deficiency?
    1. Poor memory
    2. Optic atrophy
    3. Personality change
    Select the correct answer using the code given below:
  3. Angular stomatitis and cheilosis are indicative of deficiencies of which of the following vitamins?
    1. Riboflavin
    2. Pyridoxine
    3. Thiamine
    4. Niacin
    Select the correct answer using the code given below:
  4. Confabulation is a feature of the deficiency of:
  5. All of the following are components of the Wernicke's syndrome EXCEPT:
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