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Question

The parameters used in modified Child-Pugh classification for staging cirrhosis are:

The correct answer is
Serum albumin, Serum bilirubin, prothrombin time, ascities, hepatic encephalopathy

Child-Pugh Classification Parameters

The modified Child-Pugh classification is used to assess the severity of liver disease, particularly cirrhosis, and to predict prognosis.

Key Parameters for Staging Cirrhosis

The classification utilizes a combination of laboratory values and clinical assessments. The essential parameters included in the modified Child-Pugh score are:

  • Serum Albumin: Measures the liver's synthetic function. Lower levels indicate poorer function.
  • Serum Bilirubin: Indicates the liver's ability to process and excrete bilirubin. Higher levels suggest impaired function.
  • Prothrombin Time (PT)/INR: Reflects the liver's production of clotting factors. Prolonged PT/INR indicates reduced synthetic capacity.
  • Ascites: The presence and severity of fluid accumulation in the abdomen, assessed clinically.
  • Hepatic Encephalopathy: Refers to the neurological complications arising from liver failure, assessed clinically based on severity.

Each parameter is assigned points based on its value or clinical presence, contributing to the overall Child-Pugh score, which helps in staging the disease severity.

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Important Questions from Liver Diseases

  1. Which of the following Ascitic Fluid analysis is most compatible with a diagnosis of Ascites secondary to portal hypertension?
  2. The gold standard for diagnosis of Wilson's disease is:
  3. The recent classification system for listing a patient as a candidate for liver transplantation is:
  4. The blood supply of liver consists of:
  5. A gentleman of 48 years was being worked up for hepatocellular function. He had no history or signs of encephalopathy. His serum bilirubin was 5 mg%, serum albumin was 3.9 gm%, International normalized ratio was 1.6. On ultrasound no free fluid was detected inside abdomen.
    As per Child-Turcotte-Pugh (CTP) classification, he was in:
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