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Question

A gentleman of 48 years was being worked up for hepatocellular function. He had no history or signs of encephalopathy. His serum bilirubin was 5 mg%, serum albumin was 3.9 gm%, International normalized ratio was 1.6. On ultrasound no free fluid was detected inside abdomen.
As per Child-Turcotte-Pugh (CTP) classification, he was in:

The correct answer is
CTP-B

To determine the classification of liver function impairment using the Child-Turcotte-Pugh (CTP) classification, it is important to assess specific clinical and laboratory parameters. The CTP score helps to evaluate the prognosis of chronic liver disease, mainly cirrhosis. The parameters used include:

  • Serum bilirubin
  • Serum albumin
  • International Normalized Ratio (INR)
  • Ascites
  • Hepatic encephalopathy

According to the CTP classification, each category is scored from 1 to 3, with higher scores indicating more severe disease. The scores are then summed to categorize liver function into class A, B, or C. Here's how the scoring works:

Parameter1 Point2 Points3 Points
Serum Bilirubin (mg%)<22-3>3
Serum Albumin (gm%)>3.52.8-3.5<2.8
INR<1.71.7-2.3>2.3
AscitesNoneMildModerate to Severe
EncephalopathyNoneGrade 1-2Grade 3-4

Given the patient's data:

  • Serum Bilirubin: 5 mg% → Score: 3
  • Serum Albumin: 3.9 gm% → Score: 1
  • INR: 1.6 → Score: 1
  • Ascites: None → Score: 1
  • Encephalopathy: None → Score: 1

The total score is \(3 + 1 + 1 + 1 + 1 = 7\).

The CTP classification is as follows:

  • CTP-A: 5-6 points
  • CTP-B: 7-9 points
  • CTP-C: 10-15 points

Therefore, with a total score of 7, the patient's liver disease is categorized as CTP-B.

The correct answer is: CTP-B.

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Important Questions from Liver Diseases

  1. Which of the following Ascitic Fluid analysis is most compatible with a diagnosis of Ascites secondary to portal hypertension?
  2. The parameters used in modified Child-Pugh classification for staging cirrhosis are:
  3. The gold standard for diagnosis of Wilson's disease is:
  4. The recent classification system for listing a patient as a candidate for liver transplantation is:
  5. The blood supply of liver consists of:
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