The non-ciliated cuboidal epithelial cells in bronchioles that secrete important defense markers are called
Club cells
Club Cells in Bronchioles
The question asks about specific cells found in the bronchioles that are non-ciliated, cuboidal, and secrete important defense markers. Let's look at the options provided.Understanding the Role of Cells in Bronchioles
The bronchioles are small airways in the respiratory system. Their lining is made up of epithelial cells which perform various functions crucial for lung health, including defense against inhaled particles and pathogens. Let's examine the characteristics of the cells mentioned in the options:- Goblet cells: These cells are primarily found in the larger airways (trachea, bronchi) and decrease in number as the airways get smaller. They secrete mucus, which traps particles. While important for defense, they are typically columnar, not cuboidal, in larger airways and are sparse or absent in terminal bronchioles.
- Basal cells: These are stem cells located at the base of the epithelium in the respiratory tract. They are responsible for regenerating other epithelial cell types after injury. They are not secretory cells producing defense markers.
- Langerhans cells: These are specialized dendritic cells, which are part of the immune system. They are found in various tissues, including the epithelium of larger airways, where they function as antigen-presenting cells. They are not epithelial cells lining the bronchioles that secrete defense markers.
- Club cells: Also known as Clara cells, these are indeed found in the bronchioles. They are cuboidal in shape and notably lack cilia. Club cells secrete various substances, including components of surfactant-like material and proteins like Club cell secretory protein (CCSP), also known as uteroglobin. CCSP acts as an immune modulator and has anti-inflammatory properties, functioning as a defense marker in the airways.
Important Questions from System Physiology Animal
Which one of the following synaptic vesicles (as observed under transmission electron microscope) contains catecholamines?
Blood hemostasis is the interplay of several intrinsic and extrinsic factors. Deficiency of some of the blood clotting factors and their clinical manifestations are listed below.
Factors
Manifestations
A.
V
i.
Hageman trait
B.
VII
ii.
Hypoconvertemia
C.
IX
iii.
Hemophilia B
D.
XII
iv.
Parahemophilia
Which one of the following options represents all correct matches?
Columns X and Y list the terms associated with gametogenesis and fertilisation.
Column X
Column Y
A
Primordial germ cells
i
Luteinizing hormone
B
Dictyate resting stage
ii
Posterior epiblast
C
Sodium channels
iii.
Male pronuclei
D
Protamines
iv
Block polyspermy
Which one of the following options represents all correct matches?
Nephrons are structural and functional units of the kidneys. Certain statements are made below about structure and function of a nephron.
A. P cells of the collecting duct are involved in Na+ reabsorption and vasopressin-stimulated water reabsorption.
B. P cells of the collecting duct are concerned with acid secretion and HCO3- transport.
C. I cells of the collecting duct are concerned with acid secretion and HCO3- transport.
D. The total length of the nephrons including collecting ducts ranges from 45 to 65 mm.
Which one of the following options has all correct statements?
Which one of the following factors inhibits renin secretion?
