Blood hemostasis is the interplay of several intrinsic and extrinsic factors. Deficiency of some of the blood clotting factors and their clinical manifestations are listed below. Factors Manifestations A. V i. Hageman trait B. VII ii. Hypoconvertemia C. IX iii. Hemophilia B D. XII iv. Parahemophilia Which one of the following options represents all correct matches?
A - (iv) B - (ii) C - (iii) D - (i)
Blood Clotting Factors and Deficiencies
Blood hemostasis is a complex process involving many factors that work together to stop bleeding. When one or more of these blood clotting factors are deficient or not working properly, it can lead to various bleeding disorders. Understanding which factor is associated with which condition is important.
Let's look at the factors and their corresponding clinical manifestations listed in the question:
- Factor A: Vi (Assuming this refers to Factor V)
- Factor B: VIIii (Assuming this refers to Factor VII)
- Factor C: IXiii (Assuming this refers to Factor IX)
- Factor D: XIIiv (Assuming this refers to Factor XII)
And the manifestations are:
- i: Hageman trait
- ii: Hypoconvertemia
- iii: Hemophilia B
- iv: Parahemophilia
Identifying Factor Deficiency Manifestations
Let's match each blood clotting factor deficiency with its correct clinical manifestation:
- Factor V (FV): Deficiency of Factor V is known as Parahemophilia, also called Owren's disease. This matches manifestation (iv).
- Factor VII (FVII): Deficiency of Factor VII is sometimes associated with reduced prothrombin conversion. While 'Hypoconvertemia' is not the most common term, Factor VII itself is also called Convertin, making this a plausible match for manifestation (ii).
- Factor IX (FIX): Deficiency of Factor IX is a well-known condition called Hemophilia B, also known as Christmas disease. This matches manifestation (iii).
- Factor XII (FXII): Deficiency of Factor XII is often called Hageman Factor Deficiency, and its associated condition is the Hageman trait. This typically matches manifestation (i).
Matching Factors to Manifestations
Based on the known associations, we can make the following matches:
- Factor A (Factor V) → (iv) Parahemophilia
- Factor B (Factor VII) → (ii) Hypoconvertemia
- Factor C (Factor IX) → (iii) Hemophilia B
- Factor D (Factor XII) → (i) Hageman trait
Let's present this as a table for clarity:
| Factor | Manifestation |
|---|---|
| A (Factor V) | (iv) Parahemophilia |
| B (Factor VII) | (ii) Hypoconvertemia |
| C (Factor IX) | (iii) Hemophilia B |
| D (Factor XII) | (i) Hageman trait |
Comparing these matches with the options provided, we are looking for the option that shows: A - (iv), B - (ii), C - (iii), D - (i).
The option that represents all correct matches is the one where A is matched with (iv), B with (ii), C with (iii), and D with (i).
Important Questions from System Physiology Animal
Which one of the following synaptic vesicles (as observed under transmission electron microscope) contains catecholamines?
Columns X and Y list the terms associated with gametogenesis and fertilisation.
Column X
Column Y
A
Primordial germ cells
i
Luteinizing hormone
B
Dictyate resting stage
ii
Posterior epiblast
C
Sodium channels
iii.
Male pronuclei
D
Protamines
iv
Block polyspermy
Which one of the following options represents all correct matches?
Nephrons are structural and functional units of the kidneys. Certain statements are made below about structure and function of a nephron.
A. P cells of the collecting duct are involved in Na+ reabsorption and vasopressin-stimulated water reabsorption.
B. P cells of the collecting duct are concerned with acid secretion and HCO3- transport.
C. I cells of the collecting duct are concerned with acid secretion and HCO3- transport.
D. The total length of the nephrons including collecting ducts ranges from 45 to 65 mm.
Which one of the following options has all correct statements?
The non-ciliated cuboidal epithelial cells in bronchioles that secrete important defense markers are called
Which one of the following factors inhibits renin secretion?
