Blood hemostasis is the interplay of several intrinsic and extrinsic factors. Deficiency of some of the blood clotting factors and their clinical manifestations are listed below. Factors Manifestations A. V i. Hageman trait B. VII ii. Hypoconvertemia C. IX iii. Hemophilia B D. XII iv. Parahemophilia Which one of the following options represents all correct matches?
A - (iv) B - (ii) C - (iii) D - (i)
Blood Clotting Factors and Deficiencies
Blood hemostasis is a complex process involving many factors that work together to stop bleeding. When one or more of these blood clotting factors are deficient or not working properly, it can lead to various bleeding disorders. Understanding which factor is associated with which condition is important.
Let's look at the factors and their corresponding clinical manifestations listed in the question:
- Factor A: Vi (Assuming this refers to Factor V)
- Factor B: VIIii (Assuming this refers to Factor VII)
- Factor C: IXiii (Assuming this refers to Factor IX)
- Factor D: XIIiv (Assuming this refers to Factor XII)
And the manifestations are:
- i: Hageman trait
- ii: Hypoconvertemia
- iii: Hemophilia B
- iv: Parahemophilia
Identifying Factor Deficiency Manifestations
Let's match each blood clotting factor deficiency with its correct clinical manifestation:
- Factor V (FV): Deficiency of Factor V is known as Parahemophilia, also called Owren's disease. This matches manifestation (iv).
- Factor VII (FVII): Deficiency of Factor VII is sometimes associated with reduced prothrombin conversion. While 'Hypoconvertemia' is not the most common term, Factor VII itself is also called Convertin, making this a plausible match for manifestation (ii).
- Factor IX (FIX): Deficiency of Factor IX is a well-known condition called Hemophilia B, also known as Christmas disease. This matches manifestation (iii).
- Factor XII (FXII): Deficiency of Factor XII is often called Hageman Factor Deficiency, and its associated condition is the Hageman trait. This typically matches manifestation (i).
Matching Factors to Manifestations
Based on the known associations, we can make the following matches:
- Factor A (Factor V) → (iv) Parahemophilia
- Factor B (Factor VII) → (ii) Hypoconvertemia
- Factor C (Factor IX) → (iii) Hemophilia B
- Factor D (Factor XII) → (i) Hageman trait
Let's present this as a table for clarity:
| Factor | Manifestation |
|---|---|
| A (Factor V) | (iv) Parahemophilia |
| B (Factor VII) | (ii) Hypoconvertemia |
| C (Factor IX) | (iii) Hemophilia B |
| D (Factor XII) | (i) Hageman trait |
Comparing these matches with the options provided, we are looking for the option that shows: A - (iv), B - (ii), C - (iii), D - (i).
The option that represents all correct matches is the one where A is matched with (iv), B with (ii), C with (iii), and D with (i).
Important Questions from System Physiology Animal
Which one of the following synaptic vesicles (as observed under transmission electron microscope) contains catecholamines?
Aldosterone is synthesized exclusively in zona glomerulosa due to the presence of _________ enzyme in addition to a dehydrogenase.
How much hemoglobin is present approximately in each normal human red blood cell?
The sensory nerve fibers (Column X) and the sensory receptors connected to different sensory nerves (Column Y) are given below.
Column X
Column Y
Sensory nerve fibre
Sensory receptor
A.
la
i.
Muscle spindle, flower spray ending
B.
Ib
ii.
Pain and cold receptor
C.
II
iii.
Muscle spindle, annulo-spiral ending
D.
III
iv.
Golgi tendon organ
Which of the following options represents the correct match between column X and column Y?
Given below are statements about the Kallmann syndrome.
A. It is a condition of hypogonadotropic hypogonadism.
B. There is a loss of sense of smell in such individuals.
C. This syndrome is most common in women.
D. It happens due to mutation of the KALIG1 gene on X-chromosome that codes for an adhesion molecule necessary for the normal development of the gustatory nerve.
Which one of the following options has the combination of all correct statements?
