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Question

The following are common causes of seizures in adults older than 60 years of age $except$ :

The correct answer is
Mesial temporal lobe sclerosis

Seizure Causes in Older Adults

Seizures in adults over 60 years old often stem from acquired brain injuries or conditions more prevalent in this age group. Common causes include:

  • Cerebrovascular disease: Strokes (ischemic or hemorrhagic) are a leading cause of new-onset seizures in the elderly.
  • Central nervous system neoplasia: Primary brain tumors or metastases can cause seizures.
  • Degenerative disease: Conditions like Alzheimer's disease or other dementias are associated with increased seizure risk.

Identifying the Exception

The question asks to identify the cause that is less common or not typically considered a primary cause of new-onset seizures specifically in the older adult population (>60 years) compared to the others listed.

Mesial temporal lobe sclerosis (MTLS) is a common cause of epilepsy, particularly refractory epilepsy, but it is typically diagnosed earlier in life, often following prolonged febrile seizures in childhood. While it can persist into older age, it is not considered a frequent *new* cause of seizures in the over-60 demographic relative to cerebrovascular events, tumors, or neurodegenerative processes.

Therefore, Mesial temporal lobe sclerosis is the exception among the listed common causes of seizures in adults older than 60 years.

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Important Questions from Epilepsy

  1. Consider the following with regard to trigger factors for seizures : 

    1. Flickering lights 

    2. Recreational drug misuse 

    3. Non-compliance to treatment with antiepileptic drugs 

    4. Sleep deprivation 

    Which of the factors given above are correct?

  2. Focal seizures may be associated with which of the following? 

    1. Jacksonian march 

    2. Todd's paralysis 

    3. Epilepsia partialis continua 

    Select the correct answer using the code given below.

  3. Typical absence seizures are characterized by
  4. In a young epileptic woman wishing to use oral contraceptive agents, which of the following drugs is not an ideal agent?
  5. Which of the following is not useful in the management of status epilepticus?
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