Question
Stored blood which has been preserved in a blood bank is deficient in which of the following coagulation factors?
The correct answer is
V and VIII
Blood Bank Storage: Coagulation Factor Loss
Blood stored in a blood bank undergoes degradation over time. This affects the concentration and activity of various components, including proteins essential for clotting.
Certain coagulation factors are more susceptible to degradation during storage; these are termed 'labile' factors. Factors V and VIII are notably labile and decrease significantly in concentration during the preservation period.
Consequently, stored blood, especially after extended periods, becomes deficient in these specific labile factors, namely Factors V and VIII.
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