Assertion (A) : Increase in synaptic strength is due to the simultaneous stimulation of pre - synaptic and post - synaptic neurons.
Reason (R) : Long term Potentiation can be induced in the laboratory by stimulating the pre - synaptic neurons with pulses of high frequency of electricity for few seconds.
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Synaptic Strength and LTP Analysis
Assertion (A) Truthfulness
The assertion states that an increase in synaptic strength occurs due to the simultaneous stimulation of pre-synaptic and post-synaptic neurons. This principle aligns with Hebbian learning, often summarized as "neurons that fire together, wire together." When both neurons involved in a synapse are active at the same time, the connection between them is strengthened. Therefore, Assertion (A) is considered true.
Reason (R) Truthfulness
The reason posits that Long-Term Potentiation (LTP) can be induced in a laboratory by stimulating pre-synaptic neurons with high-frequency electrical pulses for a short duration. LTP is a well-established phenomenon representing a persistent strengthening of synapses based on recent patterns of activity. High-frequency stimulation (HFS) is a standard method used to experimentally induce LTP in brain slices or in vivo. Thus, Reason (R) is true.
LTP as Explanation for Synaptic Strength
The relationship between Assertion (A) and Reason (R) needs to be examined. Assertion (A) describes a general principle: simultaneous stimulation strengthens synapses. Reason (R) describes a specific experimental method (LTP induction via HFS) that demonstrates and utilizes this principle. The high-frequency stimulation described in Reason (R) leads to repeated, synchronized activation of pre- and post-synaptic neurons, which is the mechanism underlying LTP and thus explains the increase in synaptic strength mentioned in Assertion (A). Therefore, Reason (R) provides a correct explanation for Assertion (A).
Final Conclusion
Based on the analysis, both Assertion (A) and Reason (R) are factually correct statements. Furthermore, the experimental procedure and phenomenon described in Reason (R) (LTP induction) directly serve as evidence and explanation for the principle stated in Assertion (A) (synaptic strengthening via simultaneous stimulation).
This corresponds to Option A: Both (A) and (R) are true, and (R) is the correct explanation of (A).
Important Questions from Nervous system
- Where is Broca’s area located ?
- Afferent and Efferent nerves are found in which of the following ?
- Which of the following are regulated by Sympathetic Nervous System ?
(a) Dilation of pupils
(b) Decreased activity of Adrenal Gland
(c) Digestion is stimulated
(d) Increased Heart Rate
(e) Dryness in mouth
Code : - In which parts of brain the feeling of hunger and full are felt ?
- Which of the following is the final destination for much of the brain's information about emotion, before action is taken ?
