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Question

Protein A, which has strong affinity to Fc region of immunoglobulin, is extracted from

The correct answer is
Staphylococcus aureus

Source of Protein A

Protein A is a surface protein component found in certain bacteria. It is well-known for its specific ability to bind to the Fc region of immunoglobulin G (IgG) molecules from various species.

Extraction Details

  • The question asks for the organism from which Protein A is extracted.
  • Protein A's strong affinity for the Fc region of immunoglobulins is a key characteristic.
  • Among the given options, Staphylococcus aureus is the bacterium known to naturally produce Protein A.
  • This protein is widely used in biotechnology and research for purifying antibodies.

Therefore, Protein A is extracted from Staphylococcus aureus.

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Important Questions from Methods in Microbiology

  1. Which one of the following programs is used for finding distantly related (or remote) protein homologs?
  2. Which one of the following is used for global alignment of two protein sequences?
  3. Correctly match the following Bioinformatic tool/Database with its respective Utility.
    Bioinformatic tool/DatabaseUtility
    P. BLAST1. Database for 3D protein structures
    Q. Bowtie2. Tool to identify similarity of a query sequence to existing sequences available in databanks
    R. AlphaFold3. Tool to align short read DNA sequences obtained from Next-generation sequencing to a reference genome
    S. PDB4. AI tool to predict protein structures
  4. Which of the following is NOT used for generating an optimal alignment of two nucleotide sequences?
  5. Which one of the following BLAST search programs is used to identify homologs of a genomic DNA query in a protein sequence database?
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