Positron Emission Tomography (PET) scans, often using the tracer fluorodeoxyglucose (FDG), are crucial imaging tools in the preoperative staging of gastro-oesophageal tumours. They help determine the extent of the cancer and guide treatment planning.
The primary role of PET scanning in this context is to identify distant metastatic disease. This refers to cancer that has spread from the original tumour site (in the oesophagus or stomach) to other parts of the body, such as the liver, lungs, or bones. Detecting distant metastases is critical because it often changes the treatment strategy from potentially curative surgery to palliative care or systemic therapy.
PET's strength in staging gastro-oesophageal cancer lies in its ability to detect occult (hidden) distant metastases that might not be apparent on conventional imaging. Therefore, its main purpose is the detection of distant metastatic disease.
Which of the following statements are correct regarding Barrett's oesophagus?
1. It is a metaplastic change.
2. It is a risk factor for development of adenocarcinoma.
3. Ingestion of NSAIDs is the aetiological factor for its development.
4. Endoscopic mucosal resection is an effective treatment.
Select the answer using the code given below.
An air fluid level with dilated oesophagus and "bird beak" appearance in a barium swallow is diagnostic of: