Molecular Chaperones Aid Proper Protein Folding
Molecular chaperones are a crucial class of proteins found in all cellular organisms.
Their main function is to assist in the complex process of protein folding.
They ensure that newly synthesized polypeptide chains fold into their correct, functional three-dimensional shapes.
Additionally, chaperones help prevent the misfolding and aggregation of proteins, which can be harmful to the cell.
Based on this function, molecular chaperones facilitate the proper folding of newly synthesized proteins.
Important Questions from Replication Transcription Splicing and Translation
Messenger RNAs (mRNAs) translate to generate polypeptides and the translation terminates at the UGA, UAG or UAA stop codons. The AGA codon acts as additional stop codon in the mitochondria. The longest possible polypeptide(s) that can be hypothetically translated in the cytosol and/or mitochondria, from the given full length mRNA sequence (36 nucleotides) is/are
5'-AACACCAUGACCCAUGUGGCGAGACGGUAGUUAAAA- 3'
- Which of the following statements about initiation of DNA replication in eukaryotes is/are true?
Match the drugs in Group I with their mechanism of action in Group II.
Group I Group II P) Paclitaxel 1) Inhibits protein translation Q) Colchicine 2) Inhibits microtubule depolymerization R) Etoposide 3) Inhibits DNA replication S) Methotrexate 4) Alkylates DNA 5) Inhibits dihydrofolate reductase 6) Inhibits microtubule polymerization Match the enzyme (Column I) with its corresponding function (Column II).
Column I Column II P. Primase 1. RNA dependent RNA synthesis Q. Reverse transcriptase 2. DNA dependent DNA synthesis R. RNA Replicase 3. RNA dependent DNA synthesis S. DNA Polymerase III 4. DNA dependent RNA synthesis Which of the following statements regarding the below mentioned mRNA sequence is/are TRUE?
5`-UGAUGAGCCUUAACCGGGAACGAAUUUAAG-3`
