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Question

Match the entries in Group Iwith the entries in Group II.
Group IGroup II
P. RNAse P1. Polyadenylation
Q. RNase H2. Splicing
R. snRNAs3. Ribozymes
S. CstF4. DNA-RNAhybrids

The correct answer is
P-3, Q-4, R-2, S-1

Matching Group I and Group II Entries

The question requires matching components involved in RNA processing and function with their specific roles or characteristics.

Group I to Group II Matches

  • P. RNAse P matches with 3. Ribozymes. RNAse P is known to have catalytic activity originating from its RNA component, classifying it as a ribozyme.
  • Q. RNase H matches with 4. DNA-RNA hybrids. RNase H specifically degrades the RNA strand within a DNA-RNA hybrid structure.
  • R. snRNAs matches with 2. Splicing. Small nuclear RNAs (snRNAs) are crucial components of the spliceosome, essential for pre-mRNA splicing.
  • S. CstF matches with 1. Polyadenylation. Cleavage factor I (CstF) is involved in the mRNA polyadenylation process, particularly in recognizing the polyadenylation signal and facilitating cleavage.

Summary of Correct Matches

Based on the biological functions:

  • RNAse P → Ribozymes
  • RNase H → DNA-RNA hybrids
  • snRNAs → Splicing
  • CstF → Polyadenylation

This corresponds to the matching: P-3, Q-4, R-2, S-1.

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Important Questions from Replication Transcription Splicing and Translation

  1. Messenger RNAs (mRNAs) translate to generate polypeptides and the translation terminates at the UGA, UAG or UAA stop codons. The AGA codon acts as additional stop codon in the mitochondria. The longest possible polypeptide(s) that can be hypothetically translated in the cytosol and/or mitochondria, from the given full length mRNA sequence (36 nucleotides) is/are 

    5'-AACACCAUGACCCAUGUGGCGAGACGGUAGUUAAAA- 3'

  2. Which of the following statements about initiation of DNA replication in eukaryotes is/are true?
  3. Match the drugs in Group I with their mechanism of action in Group II.

    Group IGroup II
    P) Paclitaxel 1) Inhibits protein translation 
    Q) Colchicine 2) Inhibits microtubule depolymerization 
    R) Etoposide 3) Inhibits DNA replication 
    S) Methotrexate4) Alkylates DNA 
     5) Inhibits dihydrofolate reductase 
     6) Inhibits microtubule polymerization

     

  4. Match the enzyme (Column I) with its corresponding function (Column II).

    Column IColumn II
    P. Primase1. RNA dependent RNA synthesis
    Q. Reverse transcriptase2. DNA dependent DNA synthesis
    R. RNA Replicase3. RNA dependent DNA synthesis
    S. DNA Polymerase III4. DNA dependent RNA synthesis
  5. Which of the following statements regarding the below mentioned mRNA sequence is/are TRUE? 

    5`-UGAUGAGCCUUAACCGGGAACGAAUUUAAG-3`

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