Allele Frequency Calculation
First, calculate the frequency of the $A_1$ allele ($p$) using the given genotype frequencies:
The frequency of the $A_1$ allele ($p$) is calculated as: $p = f(A_1A_1) + \frac{1}{2} f(A_1A_2)$ Substituting the given values:
$p = 0.16 + \frac{1}{2} (0.48)$ $p = 0.16 + 0.24$ $p = 0.40$
Probability of Fixation by Genetic Drift
In the context of genetic drift, assuming the allele is neutral (no selection advantage), the probability of an allele eventually becoming fixed (reaching a frequency of 1.0) in the population is equal to its current frequency.
Therefore, the probability of fixation for the $A_1$ allele is its frequency, $p$.
Probability of Fixation for $A_1 = p = 0.40$.
This value ($0.40$) lies within the specified range of 0.39 to 0.41.
Important Questions from Genetic drift
- In a diploid population of N individuals, the probability of fixation of a new neutral mutation (assuming no other mutation occurs) is _________.
- Two isolated populations M and N have population sizes of 100 and 1000 individuals, respectively. The starting allele frequencies p and q are 0.5 in both populations. Assuming no selection, which one of the following is expected after 100 generations?
- A few years ago, a very small population of zebrafish became isolated by a newly built dam. As a result, which statement is most likely to be true about this population of zebrafish now?
- Which two of the following processes can result in a decline in heterozygosity in populations?
I) inbreeding; II) genetic drift; III) mutation; IV) random mating - Which of the following processes typically does NOT contribute to increase in genetic variation?
