Assertion (A) : A positive charge applied to the inside of the membrane of the neuron produced depolarization.
Reason (R) : Inside of the membrane was positively charged.
In the context of the above two statements, which one of the following is correct ?
Codes :
This question asks to evaluate an Assertion (A) and a Reason (R) regarding changes in a neuron's membrane potential.
Assertion (A) states that applying a positive charge inside the neuron membrane causes depolarization. Depolarization is defined as a change in the membrane potential that makes the inside of the cell *less negative* (or more positive) relative to the outside. Applying a positive charge directly to the inside of the membrane achieves this by increasing the positive charge concentration, thus making the membrane potential less negative. Therefore, Assertion (A) is correct.
Reason (R) states that the inside of the membrane was positively charged. In a neuron at rest, the inside of the membrane is actually *negatively* charged relative to the outside (resting potential, typically around -70mV). While the inside *becomes* transiently positive during the peak of an action potential (due to Na+ influx), this is a result of depolarization, not the resting state. As a reason explaining why *applying* a positive charge causes depolarization, this statement is incorrect. It doesn't accurately describe the initial state, nor does it logically explain the effect of an applied charge. Therefore, Reason (R) is wrong.
Since Assertion (A) is correct and Reason (R) is wrong, the correct option is the one that states (A) is correct, but (R) is wrong.
Which one of the following synaptic vesicles (as observed under transmission electron microscope) contains catecholamines?
Blood hemostasis is the interplay of several intrinsic and extrinsic factors. Deficiency of some of the blood clotting factors and their clinical manifestations are listed below.
Factors | Manifestations | ||
A. | V | i. | Hageman trait |
B. | VII | ii. | Hypoconvertemia |
C. | IX | iii. | Hemophilia B |
D. | XII | iv. | Parahemophilia |
Which one of the following options represents all correct matches?
Aldosterone is synthesized exclusively in zona glomerulosa due to the presence of _________ enzyme in addition to a dehydrogenase.
How much hemoglobin is present approximately in each normal human red blood cell?
The sensory nerve fibers (Column X) and the sensory receptors connected to different sensory nerves (Column Y) are given below.
Column X | Column Y | ||
Sensory nerve fibre | Sensory receptor | ||
A. | la | i. | Muscle spindle, flower spray ending |
B. | Ib | ii. | Pain and cold receptor |
C. | II | iii. | Muscle spindle, annulo-spiral ending |
D. | III | iv. | Golgi tendon organ |
Which of the following options represents the correct match between column X and column Y?