Assertion A: Felbamate exhibits rare occurrence of aplastic anaemia and sever hepatotoxicity.
Reason R: It is associated with the formation of reactive metabolites.
In the light of the above statements, choose the most appropriate answer from the options given below
Felbamate Toxicity: Assertion and Reason Analysis
Assertion A Analysis
Assertion A states that Felbamate shows a rare occurrence of aplastic anaemia and severe hepatotoxicity. This statement is correct. Felbamate is recognized for these potential serious side effects, although they are infrequent.
Reason R Analysis
Reason R suggests that the toxicity is associated with the formation of reactive metabolites. This statement is also correct. The metabolism of Felbamate can generate reactive intermediate compounds.
Connecting Reason to Assertion
The reactive metabolites formed during Felbamate's breakdown are believed to be responsible for the cellular damage that leads to conditions like aplastic anaemia and hepatotoxicity. Therefore, Reason R provides the underlying mechanism explaining Assertion A.
Conclusion
Both Assertion A and Reason R are factually correct, and Reason R serves as the direct explanation for the adverse effects mentioned in Assertion A.
The most appropriate answer is: Both A and R are correct and R is the correct explanation of A.
Similar Questions
- What is the molar ratio [salt]/[acid] required to prepare an acetate buffer of pH 5.0 (pKa=4.76)?
- The falling sphere viscometer is also known as:
- In an o/w emulsion, mineral oil (specific gravity – 0.9) dispersed in aqueous phase having specific gravity of 1.05. If oil particles have average diameter of 5 micrometer, the external phase has viscosity of 0.5 poise and gravity constant is $981 \text{ cm/sec}^2$, What is the velocity of creaming in cm/day?
- The correct expression for Thixotropy B________, where U1 & U2 are plastic viscosity of two down curves after shearing at constant rate for t1 and t2 seconds, respectively.
- The correct expression for Langmuir isotherm is (given Y- mass of gas adsorbed per gram of adsorbent, p is pressure)
- Particle surface area can be determined by:
- If coarse powder is having size 1, then very fine powder will have size:
- Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: Compression distillation is conducted at high pressure and temperature.
Reason R: It produces pyrogen free water hence popular in pharmaceutical industries.
In the light of the above statements, choose the most appropriate answer from the options given below - Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: The small engraved area in letter like 'A', 'B' and 'O' are difficult to tablet manufacture cleanly
Reason R: Because tablet punches having engraving exhibit picking problem in compression.
In the light of the above statements, choose the most appropriate answer from the options given below - Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R
Assertion A: At high electrolyte concentration, dispersed systems becomes coagulated
Reason R: Repulsive forces among particles are greatly reduced.
In the light of the above statements, choose the most appropriate answer from the options given below
Important Questions from Mixed Topic (CUET PG)
- Who was the founder of Bolshevik Communist party?
- What is the key guide to statecraft in the realist tradition?
- Chronologically arrange the events in the Cold War period.
A. Berlin Wall is constructed
B. Communist China joins the UN
C. Soviet invasion of Czechoslovakia
D. Berlin Blockade
Choose the correct answer from the options given below: Morgenthau's principles of political realism are:
A. Politics is rooted in permanent and unchanging human nature which is basically self centred, self-regarding and self-interested
B. Politics is an autonomous sphere of action and cannot therefore be reduced to morals
C. International Politics is an arena of conflicting self-interests
D. The ethics of international relations is situational ethics which is very different from private morality
Choose the correct answer from the options given below:Who among the following political thinkers consider the anarchical self help system to be a compelling factor for States to maximise their relative power positions?
