Assertion A: Felbamate exhibits rare occurrence of aplastic anaemia and sever hepatotoxicity.
Reason R: It is associated with the formation of reactive metabolites.
In the light of the above statements, choose the most appropriate answer from the options given below
Felbamate Toxicity: Assertion and Reason Analysis
Assertion A Analysis
Assertion A states that Felbamate shows a rare occurrence of aplastic anaemia and severe hepatotoxicity. This statement is correct. Felbamate is recognized for these potential serious side effects, although they are infrequent.
Reason R Analysis
Reason R suggests that the toxicity is associated with the formation of reactive metabolites. This statement is also correct. The metabolism of Felbamate can generate reactive intermediate compounds.
Connecting Reason to Assertion
The reactive metabolites formed during Felbamate's breakdown are believed to be responsible for the cellular damage that leads to conditions like aplastic anaemia and hepatotoxicity. Therefore, Reason R provides the underlying mechanism explaining Assertion A.
Conclusion
Both Assertion A and Reason R are factually correct, and Reason R serves as the direct explanation for the adverse effects mentioned in Assertion A.
The most appropriate answer is: Both A and R are correct and R is the correct explanation of A.
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Important Questions from Mixed Topic (CUET PG)
- Kalpsutra, the illustrated canonical text is from:-
- The Harappan city almost exclusively devoted to craft production was-:
- Mohandas Karamchand Gandhi launched quit India movement after the failure of:-
- The "Objectives Resolution" was introduced in constituent assembly by:-
- Who among the following was not a member of the constituent assembly:-
