Consider the following statements with regard to giardiasis : 1. Stools should be examined for cysts at 2-3 days interval for its diagnosis. 2. Colonoscopy aspirate gives the highest diagnostic yield. 3. Infection usually occurs by ingesting contaminated water. 4. Giardia has a flagellate trophozoite form. Which of the statements given above are correct?
Statement 1 is correct. Diagnosing giardiasis often requires examining multiple stool samples, typically collected over several days (e.g., 2-3 days apart). This increases the likelihood of detecting Giardia cysts, improving diagnostic accuracy.
Statement 3 is correct. The primary mode of transmission for Giardia infection is the ingestion of water or food contaminated with Giardia cysts. This fecal-oral route is the most common way the parasite spreads.
Statement 4 is correct. The Giardia parasite exists in two forms: cysts (infectious stage) and trophozoites (active feeding stage). The trophozoite form is characterized by its pear shape and the presence of flagella, which enable motility within the host's small intestine.
Statement 2 is incorrect. While duodenal aspiration can be used for diagnosis, colonoscopy aspirate is not considered the method with the highest diagnostic yield for Giardiasis. Standard stool examination and antigen tests are more common and often sufficient.
Based on the analysis, statements 1, 3, and 4 are correct regarding giardiasis.
Which of the following pharmacological agents can be used for the treatment of visceral Leishmaniasis?
1. Pentavalent antimonials
2. Amphotericin B
3. Spiramycin
4. Paromomycin
Select the correct answer using the code given below: