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Question

Consider the following statements with regard to coccidioidomycosis: 

1. It is a primary systemic mycosis caused by dimorphic fungi Cocci- dioides immitis and Coccidioides posadasii. 

2. Primary pulmonary coccidioido- mycosis presents with cough, fever, chest pain and arthritis. 

3. Progressive pulmonary coccidioido- mycosis presents with constitu- tional symptoms like fever, weight loss, anorexia and features of lobar pneumonia. 

4. Coccidioides meningitis is a mild disease, not warranting any treatment. 

Which of the statements given above are correct?

The correct answer is
1, 2 and 3

Coccidioidomycosis Statements Analysis

This question asks to identify the correct statements about coccidioidomycosis, a fungal infection.

Statement 1 Evaluation

Statement 1: It is a primary systemic mycosis caused by dimorphic fungi Coccidioides immitis and Coccidioides posadasii.

  • Coccidioidomycosis is accurately described as a primary systemic mycosis.
  • The infection is caused by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii.
  • Thus, Statement 1 is correct.

Statement 2 Evaluation

Statement 2: Primary pulmonary coccidioidomycosis presents with cough, fever, chest pain and arthritis.

  • The initial phase, primary pulmonary coccidioidomycosis, often causes flu-like symptoms.
  • Common symptoms include cough, fever, chest pain, and joint pain (arthritis).
  • Therefore, Statement 2 is correct.

Statement 3 Evaluation

Statement 3: Progressive pulmonary coccidioidomycosis presents with constitutional symptoms like fever, weight loss, anorexia and features of lobar pneumonia.

  • When the infection progresses within the lungs, it leads to more severe symptoms.
  • These include constitutional signs such as fever, significant weight loss, and anorexia (loss of appetite).
  • Clinical and radiological findings can mimic lobar pneumonia.
  • Consequently, Statement 3 is correct.

Statement 4 Evaluation

Statement 4: Coccidioides meningitis is a mild disease, not warranting any treatment.

  • Coccidioides meningitis is a severe complication of disseminated coccidioidomycosis.
  • It affects the brain's protective membranes and is a serious condition.
  • This condition requires prompt and often prolonged antifungal treatment. It is not mild.
  • Therefore, Statement 4 is incorrect.

Conclusion

The correct statements are 1, 2, and 3. This corresponds to Option A.

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Important Questions from Fungal Infections

  1. Which of the following opportunistic systemic mycoses is characterized by rapid development of severe tissue necrosis and emerged as specific complication associated with COVID-19 infection in India?
  2. Which of the following fungal infections is caused by dermal inoculation of the fungal agent, usually from a thorn?
  3. A patient receiving chemotherapy develops neutropenia. He presents with fever, cough, expectoration, chest pain and hemoptysis. His CT scan of chest reveals nodular infiltrates with halo sign and crescent sign. The most useful drug for treating him is
  4. Consider the following statements with regard to Amphotericin B :
    1. It is a narrow spectrum antifungal agent.
    2. It can cause nephrotoxicity.
    3. It lacks an oral preparation.
    4. Its lipid formulations are less toxic.
    Select the correct answer using the code given below:
  5. Which one of the following moulds causes mucormycosis, commonly known as 'black fungus'?
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