1. Idiopathic membranous nephropathy has strong association with HLA - DRw3.
2. Microscopic haematuria is commonly detected in 60% of patients.
3. Hypertension is a common association.
4. Renal vein thrombosis may occur in nearly 50% of patients.
Which of the statements given above are correct ?
To determine the correct statements regarding membranous nephropathy, let's analyze each statement:
Statement 1 is correct. Idiopathic membranous nephropathy, the most common form, shows a significant association with the HLA-DRw3 antigen.
Statement 2 is incorrect. While microscopic haematuria can occur, it is typically found in a smaller percentage of patients, often around 20-30%, not the stated 60%.
Statement 3 is correct. Hypertension is a common clinical finding and complication in patients with membranous nephropathy.
Statement 4 is correct. Renal vein thrombosis is a recognized complication of membranous nephropathy, and its occurrence can be significant, sometimes cited in up to 50% of cases, especially in patients with nephrotic syndrome.
Based on the analysis, statements 1, 3, and 4 are correct.
Therefore, the correct option is the one that includes statements 1, 3, and 4.
A 40-year-old female with nephritic range proteinuria is found to have low serum complement levels. Which of the following can be the likely etiology?
1. Systemic lupus erythematosus
2. Post-infectious glomerulonephritis
3. Infective endocarditis
4. Mesangio-capillary glomerulonephritis
Select the correct answer using the code given below: