This question describes a clinical scenario typical of Post-Streptococcal Glomerulonephritis (PSGN), a kidney condition often following a Group A Streptococcal infection, indicated by the history of a sore throat (indicative of a prior streptococcal throat infection), followed by symptoms like hematuria, oliguria, edema, and hypertension. Key laboratory results are low C_3 complement levels and increased anti-streptolysin O (ASO) and anti-DNase B titers, which support this diagnosis.
Let us analyze the statements:
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Renal biopsy is rarely required for making diagnosis.
This statement is correct. PSGN is typically diagnosed based on clinical presentation and lab tests, such as low C_3 and elevated ASO titers. A biopsy is generally not needed unless there's an atypical presentation. -
Antibiotic treatment is given for streptococcal infection.
This statement is correct. Though the streptococcal throat infection often resolves by the time PSGN presents, antibiotics may still be used to eradicate any residual infection and prevent transmission. -
Treatment is largely supportive.
This statement is correct. The management of PSGN largely includes supportive care such as managing hypertension and edema with antihypertensives and diuretics, rest, and monitoring kidney function. -
Immunosuppressants are to be used for crescentic glomerulonephritis.
This statement is NOT correct in the context of typical PSGN management. While crescentic glomerulonephritis is a severe form needing aggressive treatment, including immunosuppressants, these are not routinely used for standard PSGN cases unless complicated by renal impairment or rapidly progressive glomerulonephritis.
Based on the context and reasoning, the statement that is NOT correct about the management of PSGN is:
Immunosuppressants are to be used for crescentic glomerulonephritis
This option was identified based on standard treatment protocols for PSGN, which are different from those used for rapidly progressive cases where crescents are present.
Important Questions from Nephrotic Syndrome
- All of the following conditions are associated with Glomerulonephritis with low complement level, EXCEPT:
- Which of the following are the indications of Renal biopsy?
1. Chronic Kidney disease with normal sized kidney
2. Nephrotic syndrome in adults
3. Nephrotic syndrome in children with atypical features
Select the correct answer using the code given below: - Presence of Dysmorphic Erythrocytes in urine analysis is suggestive of:
A 40-year-old female with nephritic range proteinuria is found to have low serum complement levels. Which of the following can be the likely etiology?
1. Systemic lupus erythematosus
2. Post-infectious glomerulonephritis
3. Infective endocarditis
4. Mesangio-capillary glomerulonephritis
Select the correct answer using the code given below:
- Which of the following are consequences of nephrotic syndrome ?
1. Increased lipoprotein synthesis
2. Low serum globulin levels
3. Increased serum aldosterone levels
4. Increased serum Antithrombin III levels
Select the correct answer using the code given below :
