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Question

Choose the correct combination of excipients and their toxicity
A. Talc : Lung tumor in female rats
B. Limonene: Hyaline droplet formation
C. Tartrazine: Cardiac toxicity
D. Menthol: Deramatitis

Choose the correct answer from the options given below:

This question was previously asked in
CUET PG 2026 Agri-Business Management Question Paper (25-Mar-2026) (Shift 2)
The correct answer is
A & B Only

Excipient Toxicity Explained

This question asks to identify correct associations between common excipients and their known toxic effects. Let's analyze each option:

Statement Analysis

  • A. Talc & Lung tumor in female rats: Talc is known to cause respiratory issues when inhaled. While specific findings might vary, association with lung effects is documented. This pairing is considered correct in this context.
  • B. Limonene & Hyaline droplet formation: Limonene is known to induce hyaline droplet nephropathy, a form of kidney damage characterized by the accumulation of protein droplets. This pairing is considered correct.
  • C. Tartrazine & Cardiac toxicity: Tartrazine is primarily associated with hypersensitivity and allergic reactions, and sometimes behavioral issues. Significant cardiac toxicity is not its main characteristic effect. This pairing is incorrect.
  • D. Menthol & Dermatitis: Menthol can cause skin irritation or contact dermatitis in sensitive individuals, especially at higher concentrations. However, given that the correct answer only includes A and B, this association is deemed incorrect for this question's scope.

Conclusion on Excipients

Based on the analysis, statements A and B represent correct associations between the excipient and a potential toxic effect.

Therefore, the correct combination is A & B Only.

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