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Question

Based on their function, find the ODD one out.

The correct answer is
snRNA

RNA Function: Finding the Odd One Out

The question asks to identify the RNA molecule that differs in function from the others.

Functions of Listed RNAs

  • miRNA (microRNA): Primarily involved in post-transcriptional gene regulation, typically by inhibiting translation or causing degradation of messenger RNA (mRNA).
  • siRNA (small interfering RNA): Acts in gene silencing pathways, often through RNA interference (RNAi). siRNAs guide protein complexes to target specific mRNA molecules for cleavage and degradation.
  • shRNA (short hairpin RNA): Similar to siRNA, shRNAs are precursors that are processed into siRNAs. They also function in gene silencing via RNAi.
  • snRNA (small nuclear RNA): A key component of the spliceosome, the molecular machinery responsible for removing introns from pre-mRNA during RNA processing.

Reasoning

miRNA, siRNA, and shRNA all play roles in gene silencing, primarily targeting mRNA molecules after transcription.

In contrast, snRNA's main function is within the nucleus, participating in the splicing of pre-mRNA, a crucial step in RNA processing before translation can occur.

Therefore, based on function, snRNA is distinct from the gene-silencing roles of miRNA, siRNA, and shRNA.

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Important Questions from Enzyme Classification Catalytic and Regulatory Strategies

  1. Correctly match the Coenzyme with its respective involvement in a specific Reaction type.
    CoenzymeReaction type
    P. Thiamine pyrophosphate1. Acyl group transfer
    Q. Tetrahydrofolate2. Transfer of one carbon group
    R. Flavin adenine dinucleotide3. Transfer of methyl group
    S. 5'-Deoxyadenosyl cobalamin4. Oxidation-reduction
    5. Aldehyde transfer
  2. An enzyme catalyzes a reaction by
  3. The activity of an enzyme is expressed in International Units (IU). However, the S.I. unit for enzyme activity is Katal. One Katal is
  4. Match the entries inGroup I with the enzymes inGroup II.
    Group IGroup II
    P. NAD$^+$1. Glutathione peroxidase
    Q. Selenium2. Nitrogenase
    R. Pyridoxal phosphate3. Lactate dehydrogenase
    S. Molybdenum4. Glycogen phosphorylase
  5. Determine the correctness or otherwise of the following Assertion (a) and the Reason (r)

    Assertion: A very low amount of inhibitor can act as an activator for allosteric enzymes. 

    Reason: Allosteric enzymes follow Michaelis-Menten kinetics.

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