Meningomyelocoele is a severe form of spina bifida, a type of neural tube defect.
Condition Overview: It occurs when the spinal canal and the backbone do not close completely during pregnancy. This results in the spinal cord and its protective covering (meninges) bulging out through an opening in the back.
Common Site: This condition is most frequently observed in the lower part of the back.
Reasoning: The neural tube normally closes early in fetal development. Failure of closure typically happens in the caudal (lower) end of the neural tube, making the lumbosacral region the most susceptible area for defects like meningomyelocoele.
Conclusion: Therefore, the most common location for a meningomyelocoele is the lumbosacral spine.
Which of the following are correct regarding androgen insensitivity syndrome?
1. Inherited as X-linked recessive disorder
2. Karyotype is 46 XXY
3. It is also called testicular feminization
4. Confirmation of diagnosis by gonadal biopsy
Select the answer using the code given below.