Group I Group II [P] Influenza A virus 1. Isoniazid [Q] Fungus 2. Amantadine [R] Plasmodium 3. Fluconazole [S] Mycobacterium 4. Artemisinin 5. Iodoquinol
The question requires matching specific pathogens with their corresponding anti-microbial agents used for treatment.
Based on the standard treatments for these pathogens:
This corresponds to the pairing P-2, Q-3, R-4, S-1.
Match the antibiotics in Group I with their modes of action in Group II.
| Group I | Group II |
| P) Chloramphenicol | 1) Inhibits protein synthesis by acting on 30S ribosomal subunit |
| Q) Rifampicin | 2) Interferes with DNA replication by inhibiting DNA gyrase |
| R) Tetracycline | 3) Inhibits protein synthesis by acting on 50S ribosomal subunit |
| S) Quinolone | 4) Interferes with RNA polymerase activity |
| 5) Inhibits $\beta$-lactamase activity |
A bacterial culture (200 µl containing $1.8 \times 10^9$ cells) was treated with an antibiotic Z (50 µg per ml) for 4 h at 37°C. After this treatment, the culture was divided into two equal aliquots.
Set A: 100 µl was plated on Luria agar.
Set B: 100 µl was centrifuged, the cell pellet washed and plated on Luria agar.
After incubating these two plates for 24 h at 37°C, Set A plate showed no colonies, whereas the Set B plate showed $0.9 \times 10^9$ cells. This experiment showed that the antibiotic Z is