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Question

A 56-year old man presented with acute onset aphasia. Speech output was markedly reduced with preserved comprehension of spoken language. The area of brain involved is:

The correct answer is
Inferior frontal gyrus

Understanding Aphasia Localization: Inferior Frontal Gyrus

The patient presents with acute aphasia, specifically characterized by markedly reduced speech output but preserved comprehension. This pattern indicates expressive aphasia (also known as Broca's aphasia or motor aphasia).

Identifying the Affected Brain Region

  • Expressive aphasia results from damage to the brain regions responsible for speech production.
  • The inferior frontal gyrus, particularly the dominant hemisphere's posterior portion (Broca's area), is critical for motor planning and execution of speech.
  • Damage to this specific area directly impairs the ability to produce fluent speech, aligning with the symptom of "markedly reduced speech output."
  • Conversely, the posterior part of the temporal lobe (Wernicke's area) is associated with language comprehension. Damage here leads to receptive aphasia, which is inconsistent with the patient's preserved comprehension. The cerebellum and midbrain are not primarily involved in language production.

Therefore, the affected brain area is the inferior frontal gyrus.

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