The question asks for the primary medication used to induce remission in Minimal Change Nephrotic Syndrome (MCNS) for a 5-year-old boy.
Drug Choice for MCNS Remission Induction
Minimal Change Nephrotic Syndrome (MCNS) is the most common cause of nephrotic syndrome in young children. The standard initial treatment focuses on inducing remission, which means stopping the loss of protein in the urine.
- Prednisolone is a corticosteroid and is considered the first-line drug of choice for inducing remission in MCNS. It effectively reduces proteinuria and helps the child recover.
Evaluating Other Options
The other medications listed are not the primary choice for initial remission induction:
- Furosemide is a diuretic used to manage fluid overload (edema) but does not treat the underlying cause of MCNS.
- Cyclophosphamide is an immunosuppressant that may be used later for frequent relapses or steroid-dependent cases, but it is not the initial drug for induction due to potential side effects.
- Levamisole is another immunomodulatory drug sometimes considered for steroid-resistant cases, not the first-line induction therapy.
Therefore, Prednisolone is the most appropriate choice for initiating treatment to achieve remission in Minimal Change Nephrotic Syndrome.
Important Questions from Nephrotic Syndrome
A 40-year-old female with nephritic range proteinuria is found to have low serum complement levels. Which of the following can be the likely etiology?
1. Systemic lupus erythematosus
2. Post-infectious glomerulonephritis
3. Infective endocarditis
4. Mesangio-capillary glomerulonephritis
Select the correct answer using the code given below:
- All of the following conditions are associated with Glomerulonephritis with low complement level, EXCEPT:
- Which of the following are the indications of Renal biopsy?
1. Chronic Kidney disease with normal sized kidney
2. Nephrotic syndrome in adults
3. Nephrotic syndrome in children with atypical features
Select the correct answer using the code given below: - Presence of Dysmorphic Erythrocytes in urine analysis is suggestive of:
- Of all the types of lupus nephritis, the worst outcome is seen in:
