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Question

Which one of the following is the minimum spirometry criterion for diagnosis of bronchial asthma?

The correct answer is

Increase in FEV1  $ \geq$12% following administration of inhaled bronchodilators

Diagnostic Spirometry for Bronchial Asthma

Spirometry is a key tool for diagnosing respiratory conditions like bronchial asthma. It measures lung function, specifically the amount and speed of air inhaled and exhaled. For diagnosing bronchial asthma, the focus is often on the reversibility of airflow obstruction.

Assessing Airflow Reversibility

A crucial spirometry criterion involves measuring the change in Forced Expiratory Volume in 1 second (FEV1) after administering a short-acting inhaled bronchodilator. A significant improvement in FEV1 indicates that the airflow obstruction is reversible, a hallmark characteristic of asthma.

Minimum Diagnostic Criterion

  • The standard minimum criterion for diagnosing bronchial asthma using spirometry is an increase in FEV1 of $ \geq 12\% $ (percent) after the administration of inhaled bronchodilators.

This demonstrates reversible airflow obstruction, distinguishing asthma from other obstructive lung diseases where obstruction may be fixed or less responsive to bronchodilators.

Evaluating Other Options

  • A decrease in FEV1 after exercise (Option 1) can be part of an exercise challenge test for asthma but isn't the primary diagnostic spirometry criterion for reversible obstruction.
  • Changes after glucocorticoids (Option 3) relate more to treatment response than initial diagnosis.
  • Diurnal variation in Peak Expiratory Flow (PEF) (Option 4) is a characteristic feature of asthma, but the FEV1 response to bronchodilators is a more direct spirometric measure of reversibility for diagnosis.
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Important Questions from Asthma

  1. Which of the following does NOT cause pulmonary infiltrates with eosinophilia?
  2. Oral corticosteroids are best introduced in the treatment of chronic bronchial asthma when it is:
  3. A 26-year old young lady attends medical emergency and is labelled as acute severe asthma by the emergency physician. Which one of the following is unlikely to be a part of the prescription?
  4. All of the following are Long Acting Beta Agonists (LABA) EXCEPT:
  5. Which one of the following is used to distinguish narrowing of large airway from small airway?

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