Question
Which one of the following drugs is a Direct Renin Inhibitor?
The correct answer is
Aliskiren
Direct Renin Inhibitor Drug Identification
The question asks to identify the drug that acts as a Direct Renin Inhibitor from the given options.
Drug Class Analysis
- Benedipine: This is a calcium channel blocker used for treating hypertension. It does not directly inhibit renin.
- Azilsartan: This is an Angiotensin II Receptor Blocker (ARB). ARBs block the action of angiotensin II but do not inhibit renin directly.
- Aliskiren: This drug directly binds to the active site of renin and inhibits its enzymatic activity, thus blocking the Renin-Angiotensin-Aldosterone System (RAAS) at its initial step.
- Lisinopril: This is an Angiotensin-Converting Enzyme (ACE) inhibitor. ACE inhibitors prevent the conversion of angiotensin I to angiotensin II, but they do not inhibit renin itself.
Conclusion
Based on the mechanism of action, Aliskiren is the only drug among the options that functions as a Direct Renin Inhibitor.
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Important Questions from Hypertension
- All of the following are causes of systolic hypertension with wide pulse pressure EXCEPT:
- Drug of choice for treating hypertensive emergency in a case of Aortic dissection is:
- The preferred anti hypertensive drug for a 74 year old male with benign prostatic hypertrophy is:
- The following are features of polycythaemia vera EXCEPT:
- Which of the following are non –modifiable risk factors for hypertension?
1. Age
2. Sex
3. Genetic factors
Select the correct answer using the code given below:
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