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Question

Which one among the following essential amino acids is usually the "limiting" amino acid in most of the pulses ?

The correct answer is
Methionine

Understanding the Limiting Amino Acid in Pulses

This question asks us to identify which essential amino acid is typically found in the smallest relative amount in pulses, thereby limiting protein synthesis. Pulses, such as lentils, beans, and peas, are a significant source of protein in many diets, especially vegetarian ones. However, like most plant-based foods, their protein quality is often assessed by their essential amino acid profile.

What are Essential Amino Acids and Limiting Amino Acids?

Essential amino acids are the building blocks of protein that our bodies cannot produce on their own. We must obtain them from our diet. The ten essential amino acids typically include: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.

A limiting amino acid refers to the essential amino acid that is present in the lowest concentration relative to the needs for protein synthesis. If even one essential amino acid is insufficient, it restricts the body's ability to build proteins effectively, even if other amino acids are abundant.

Amino Acid Profile of Pulses

Pulses generally have a favorable amino acid profile in many respects. They are notably rich in lysine, an amino acid often found in low amounts in cereal grains. This makes pulses a valuable complement to diets based heavily on grains.

However, pulses are typically low in certain other essential amino acids, particularly those containing sulfur. These include methionine and cysteine.

Identifying Methionine as the Limiting Amino Acid

Given the typical amino acid composition of pulses, methionine is consistently identified as the limiting essential amino acid. While pulses are rich in lysine, they do not contain sufficient amounts of methionine to meet the body's requirements for optimal protein synthesis when consumed as the sole protein source.

Let's consider the options provided:

  • Lysine: This is generally abundant in pulses, not limiting.
  • Methionine: This is characteristically low in pulses and is therefore the limiting amino acid.
  • Threonine: While important, threonine is usually present in adequate or near-adequate amounts in pulses relative to other limiting amino acids.
  • Valine: Similar to threonine, valine is generally not considered the primary limiting amino acid in pulses.

Therefore, methionine is the essential amino acid that typically limits the protein quality of most pulses. Combining pulses with other food groups, like cereals (which are often limiting in lysine but richer in methionine), can create a more complete protein profile.

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Important Questions from Miscellaneous

  1. A 35 year old male presents with increased urine output. On evaluation, his urinary output was around 4L/day; urinary osmolality was 200 mosmol/L. Which of the following are various differential diagnosis ?

    I. Psychogenic polydipsia

    II. Solute diuresis

    III. Central diabetes insipidus

    IV. Nephrogenic diabetes insipidus

    Select the correct answer using the
    code given below:

  2. Which one of the following causes low-volume erythrocytosis?

  3. Under which one of the following conditions, the HPA axis suppression is likely to result in crisis due to adrenal insufficiency following withdrawal of glucocorticoids?

  4. A 36 year old man presents with decreased apetite, mouth soreness, diarrhoea and irritability. On examination he has a bright red tongue with a pigmented scaly rash around the neck. Which one of the following food items in his diet has a bearing on his disease?

  5. Koebner phenomenon is seen in which one of the following conditions?

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