This question asks us to identify which essential amino acid is typically found in the smallest relative amount in pulses, thereby limiting protein synthesis. Pulses, such as lentils, beans, and peas, are a significant source of protein in many diets, especially vegetarian ones. However, like most plant-based foods, their protein quality is often assessed by their essential amino acid profile.
Essential amino acids are the building blocks of protein that our bodies cannot produce on their own. We must obtain them from our diet. The ten essential amino acids typically include: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.
A limiting amino acid refers to the essential amino acid that is present in the lowest concentration relative to the needs for protein synthesis. If even one essential amino acid is insufficient, it restricts the body's ability to build proteins effectively, even if other amino acids are abundant.
Pulses generally have a favorable amino acid profile in many respects. They are notably rich in lysine, an amino acid often found in low amounts in cereal grains. This makes pulses a valuable complement to diets based heavily on grains.
However, pulses are typically low in certain other essential amino acids, particularly those containing sulfur. These include methionine and cysteine.
Given the typical amino acid composition of pulses, methionine is consistently identified as the limiting essential amino acid. While pulses are rich in lysine, they do not contain sufficient amounts of methionine to meet the body's requirements for optimal protein synthesis when consumed as the sole protein source.
Let's consider the options provided:
Therefore, methionine is the essential amino acid that typically limits the protein quality of most pulses. Combining pulses with other food groups, like cereals (which are often limiting in lysine but richer in methionine), can create a more complete protein profile.
A 42-year old man with history of alcohol dependency presents with progressive abdominal distension. Abdominal examination reveals a
shifting dullness. Which one of the following is the most appropriate drug to relieve this abdominal distension?
Which one of the following is the investigation of choice for diagnosing the presence of stones in the gall-bladder?
Which one of the following biologic agents used in the treatment of inflammatory Bowel Disease acts by inhibiting the enzyme 'Janus Kinase'?
Melanosis coli, which occurs due to long term consumption of stimulant laxatives, presents as brown dis-colouration of colonic mucosa due to
deposition of which one of the following pigments?
Consider the following with regard to Gilbert Syndrome:
I. Autosomal recessive trait of a mutation in gene for UDP- glucuronyl transferase enzyme
II. Elevation of unconjugated bilirubin
III. No stigmata of chronic liver disease other than jaundice
IV. Early Liver biopsy recommended in patients with possible Gilbert Syndrome
Which of the above are correct?