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Question

Which of the following statements about peptic ulcers is correct?

The correct answer is
Anteriorly located duodenal ulcers are 'more prone for perforation'.

Peptic Ulcer Characteristics Explained

Understanding the key features of peptic ulcers is crucial. Let's evaluate each statement:

  • Statement 1: Location Incorrect
    The most common site for duodenal ulcers is the proximal (first part) of the duodenum, not the third part. Gastric ulcers have different common locations.
  • Statement 2: Gender Prevalence Incorrect
    Peptic ulcers, particularly duodenal ulcers, are generally more common in males than females. While H. pylori infection rates might be similar, other factors influence ulcer development differently across genders.
  • Statement 3: Malignancy Risk Incorrect
    Gastric ulcers carry a risk of becoming malignant (developing into cancer). Therefore, the statement that there is no risk of malignancy is false. Duodenal ulcers, however, rarely become malignant.
  • Statement 4: Perforation Risk Correct
    Anteriorly located duodenal ulcers are indeed more susceptible to perforation, where the ulcer erodes completely through the anterior wall of the duodenum, potentially leading to leakage into the abdominal cavity. Posterior ulcers have different complications, such as penetration into adjacent organs like the pancreas.

Key Takeaway

The critical risk associated with the location of a duodenal ulcer is highlighted in the correct statement: anterior ulcers have a higher likelihood of perforation.

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Important Questions from Stomach

  1. A 50 year old male patient presents to the emergency with sudden onset of upper abdominal pain, nausea, vomiting and haematemesis. On examination, PR = $106/min$, BP = $100/70$ mm Hg and pallor is present. CECT abdomen reveals a large exophytic tumor of size $13 \times 8$ cm at the fundus of the stomach. On upper GI endoscopy, the mucosa overlying the tumor is intact. The staining for CD117 in the upper GI endoscopic biopsy is positive. The most probable clinical diagnosis in this patient is
  2. The most common metabolic abnormality associated with gastric outlet obstruction is
  3. A 50 year old male patient presents to the emergency with sudden onset of upper abdominal pain, nausea, vomiting and haematemesis. On examination, PR = $106$/min, BP = $100/70$ mm Hg and pallor is present. CECT abdomen reveals a large exophytic tumor of size $13 \times 8$ cm at the fundus of the stomach. On upper GI endoscopy, the mucosa overlying the tumor is intact. The staining for CD117 in the upper GI endoscopic biopsy is positive. The most probable clinical diagnosis in this patient is
  4. A gentleman of 36 years presented with a long history of upper abdominal pain which was periodic and often occurred early morning. For last 3 months, he is having projectile vomiting, which is non bilious, unpleasant in nature with undigested food materials. On examination he appears unwell, dehydrated and seemed to have lost weight. Probably he is suffering from:
  5. All of the following are sequelae of peptic ulcer surgery EXCEPT:
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