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Question

Which of the following is/are extra-cellular matrix protein(s)?

Identifying Extra-cellular Matrix Proteins

The extracellular matrix (ECM) provides structural and biochemical support to surrounding cells. Identifying its protein components is essential in cell biology.

Analyzing Protein Roles

Myosin

Myosin is a key intracellular motor protein essential for muscle contraction and other cellular movements. It is not found in the extracellular matrix.

Fibronectin

Fibronectin is a major glycoprotein present in the ECM. It plays vital roles in cell adhesion, cell motility, and wound healing. Therefore, Fibronectin is an ECM protein.

Lamin

Lamin proteins form the nuclear lamina, located just inside the inner membrane of the cell nucleus. They are structural components of the nucleus, not the ECM.

Collagen

Collagen is the most abundant protein in mammals and a primary structural component of the ECM. It provides tensile strength to tissues. Thus, Collagen is an ECM protein.

Conclusion on ECM Proteins

Based on the analysis:

  • Fibronectin (Option B) is an ECM protein.
  • Collagen (Option D) is an ECM protein.
  • Myosin (Option A) is an intracellular protein.
  • Lamin (Option C) is a nuclear protein.

The extra-cellular matrix proteins listed are Fibronectin and Collagen.

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