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Question

Which of the following hormones from adenohypophysis controls the function of the seminiferous tubules?

The correct answer is

Follicle - stimulating hormone (FSH)

Understanding Hormones and Seminiferous Tubules

The question asks about the hormone produced by the adenohypophysis (anterior pituitary gland) that directly influences the function of the seminiferous tubules in males. The adenohypophysis produces several important hormones that regulate various bodily functions.

Adenohypophysis Hormones and Male Reproduction

The adenohypophysis plays a crucial role in male reproduction by secreting gonadotropins:

  • Follicle-stimulating hormone ($\text{FSH}$)
  • Luteinizing hormone ($\text{LH}$)

These hormones act on the testes, which contain seminiferous tubules and interstitial cells (Leydig cells).

Function of Seminiferous Tubules

The seminiferous tubules are the primary sites within the testes where spermatogenesis, the process of sperm production, occurs. These tubules contain:

  • Sertoli cells: Also known as nurse cells, these cells support, nourish, and regulate the development of sperm. They also produce various factors, including androgen-binding protein ($\text{ABP}$).
  • Germ cells: These cells undergo meiosis and differentiation to become sperm.

How Hormones Control Seminiferous Tubules Function

Let's look at how $\text{FSH}$ and $\text{LH}$ affect the testes:

  • Luteinizing hormone ($\text{LH}$): $\text{LH}$ primarily acts on the Leydig cells (interstitial cells) located between the seminiferous tubules. Stimulation by $\text{LH}$ causes Leydig cells to produce testosterone, the main male sex hormone. Testosterone is essential for spermatogenesis and the development of male secondary sexual characteristics. While testosterone is needed for the seminiferous tubules to function effectively, $\text{LH}$'s primary target is outside the tubules themselves.
  • Follicle-stimulating hormone ($\text{FSH}$): $\text{FSH}$ acts directly on the Sertoli cells located within the walls of the seminiferous tubules. $\text{FSH}$ stimulates Sertoli cells to promote spermatogenesis and produce factors like $\text{ABP}$. By acting on Sertoli cells, $\text{FSH}$ directly controls the supportive and regulatory functions essential for sperm development within the tubules.

The question specifically asks about the hormone controlling the function of the seminiferous tubules. While both $\text{FSH}$ and $\text{LH}$ (via testosterone) are necessary for complete spermatogenesis, $\text{FSH}$ has a more direct role in stimulating and controlling the activities of the Sertoli cells, which are integral to the function of the tubules.

Conclusion

Based on their specific actions, Follicle-stimulating hormone ($\text{FSH}$) from the adenohypophysis directly controls the function of the seminiferous tubules by targeting the Sertoli cells, promoting spermatogenesis and support functions.

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Important Questions from Glands and Hormones

  1. Which of the following is not a steroid hormone?

  2. Oxytocin is secreted by the _______.

  3. Secretion of adrenaline hormone causes nervousness and irritability as an effect of which of the following?

  4. The thyroid glands produces a hormone called _______.

  5. Testosterone is a _______ hormone.

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