Question
Which of the following enzymes synthesizes precursor mRNA ?
This question was previously asked in
NEET UG Re-Exam 2026 Question Paper (21-Jun-2026)
The correct answer is
RNA polymerase II
Enzyme Synthesizing Precursor mRNA
The synthesis of precursor messenger RNA (pre-mRNA) in eukaryotic cells is primarily carried out by a specific enzyme.
RNA Polymerase II Function
RNA polymerase II is the key enzyme responsible for transcribing protein-coding genes. It synthesizes the initial RNA transcript, known as pre-mRNA, which contains introns and exons.
Processing of Pre-mRNA
This pre-mRNA molecule subsequently undergoes several processing steps, including splicing (removal of introns), 5' capping, and 3' polyadenylation, to become mature messenger RNA (mRNA) ready for translation.
Other RNA Polymerases
- RNA polymerase I is mainly involved in synthesizing ribosomal RNA (rRNA).
- RNA polymerase III synthesizes transfer RNA (tRNA), 5S rRNA, and other small RNAs.
- DNA polymerase is involved in DNA replication, not RNA synthesis.
Conclusion
Therefore, RNA polymerase II is the enzyme that synthesizes precursor mRNA.
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Important Questions from Molecular Biology
- Arrange the following steps of DNA fingerprinting in a correct sequence.
A. Isolation of DNA and its digestion by restriction endonucleases.
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C. Transferring of separated DNA fragments to synthetic membranes.
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E. Separation of DNA fragments by electrophoresis.
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A. Histones are organized to form a unit of eight molecules called histone octamer.
B. Histones are negatively charged basic proteins.
C. Histones are rich in the basic amino acid residues - lysine and arginine.
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E. The packaging of chromatin at higher levels requires an additional set of proteins called non-histone chromosomal proteins.
Choose the correct answer from the options given below : - The correct statement with regard to the secondary structure of DNA/RNA is :
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C. The promoter is a DNA sequence that provides binding site for RNA polymerase.
D. The promoter defines the template and coding strands.
E. The terminator is located towards the 3'-end of the coding strand and it defines the end of the process of transcription.
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