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Question

Which of the following drugs is safest in pregnancy hypertension?

The correct answer is Labetalol

The correct answer is Labetalol.

Labetalol, a combined alpha- and beta-blocker, lowers BP without reducing uteroplacental blood flow and is a first-line antihypertensive in pregnancy (with methyldopa and nifedipine); IV labetalol is used in hypertensive emergencies.

Enalapril and captopril (ACE inhibitors) are contraindicated – they cause fetal renal damage, oligohydramnios, skull hypoplasia and growth restriction. Propranolol is associated with fetal growth restriction, neonatal bradycardia and hypoglycaemia, so it is not preferred.

Short trick: Pregnancy BP: "Labetalol, Methyldopa, Nifedipine" – never ACE inhibitors.

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Important Questions from Medical Surgical Nursing

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