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Question

Which of the following conditions may produce "wrist drop"?

The correct answer is
Lead poisoning

Understanding Wrist Drop Causes

Wrist drop refers to the inability to lift the hand due to weakness or paralysis in the muscles that extend the wrist and fingers. This condition primarily results from damage or dysfunction affecting the radial nerve, which controls these specific movements.

Analyzing Potential Causes of Wrist Drop

The question asks which condition can cause wrist drop. Let's evaluate the options:

  • Lead poisoning: Chronic exposure to lead is known to cause peripheral neuropathy. It can specifically damage the radial nerve, leading to the characteristic symptoms of wrist drop.
  • Diabetes mellitus: While diabetes can cause nerve damage (diabetic neuropathy), wrist drop is not a common or typical symptom. Foot drop and sensory disturbances are more frequently associated with diabetic neuropathy.
  • Alcoholics: Long-term excessive alcohol consumption can lead to alcoholic neuropathy. Although peripheral nerves can be affected, isolated wrist drop is less commonly cited as a primary symptom compared to other neurological issues.
  • Beriberi: This condition arises from a deficiency in thiamine (Vitamin B1). While it causes neurological problems, including peripheral neuropathy, wrist drop is not considered a hallmark symptom.

Identifying the Correct Cause

Considering the direct effects on the radial nerve, lead poisoning is the most likely condition among the choices to produce wrist drop.

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Important Questions from Brain & Nervous System Surgery

  1. The term mid-line shift is associated with:
  2. In diffuse axonal injury all are true EXCEPT:
  3. A 70 years old man on anticoagulants due to some heart disease suffered a minor head injury. One month later he has severe headache with slowly developing neurological signs. The probable diagnosis is:
  4. A patient with suspected head injury is brought to the emergency following road traffic accident. At the time of examination, patient is conscious with GCS 14/15 and stable vitals. There is bleeding from right ear and CSF leak from nose. Bruising is present behind the right ear. The most probable clinical diagnosis in this patient is
  5. A comatose patient after sustaining severe head injury has been admitted in neurosurgical ICU. Which of the following parameters should ideally be maintained in this patient ?
    1. pCO$_2$ = 4.5 – 5.0 kPa (33-38 mm Hg)
    2. MAP = 80 – 90 mm of Hg
    3. pO$_2$ > 11 kPa (> 80 mm Hg)
    4. Na$^+$ < 130 meq/L
    Select the correct answer using the code given below :
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