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Question

Which of the following are suggestive of Parkinson's disease ?
1. Lead pipe rigidity
2. Cog wheel rigidity
3. Festinating gait
4. Romberg test positive
Select the correct answer using the code given below :

The correct answer is
1, 2 and 3

The question asks which of the given signs are suggestive of Parkinson's disease. Parkinson's disease is a chronic neurodegenerative disorder caused by loss of dopaminergic neurons in the substantia nigra, leading to the cardinal motor features of rigidity, bradykinesia, resting tremor, and postural instability.

Analysis of Each Statement

  • 1. Lead pipe rigidity: This is a uniform, continuous resistance felt throughout the range of passive movement of a limb, without the ratchet-like interruptions. It is one of the classic forms of rigidity seen in Parkinson's disease and is correct.
  • 2. Cog wheel rigidity: This is a jerky, ratchet-like resistance to passive movement, produced by rigidity superimposed on an underlying tremor. It is a hallmark, highly specific sign of Parkinson's disease and is correct.
  • 3. Festinating gait: A characteristic gait abnormality in Parkinson's disease consisting of stooped posture, short shuffling steps, reduced arm swing, and an involuntary tendency to accelerate (festination). This is correct and one of the most recognizable clinical features of the disease.
  • 4. Romberg test positive: A positive Romberg sign reflects loss of proprioceptive or vestibular input (e.g., sensory ataxia, posterior column disease, vestibular disorders) rather than an extrapyramidal movement disorder. Parkinson's disease causes postural instability due to loss of postural reflexes, but this is tested clinically by the "pull test," not the Romberg test, and Parkinson's patients are typically Romberg-negative since their proprioceptive pathways are intact. This statement is incorrect.

Conclusion

Lead pipe rigidity, cog wheel rigidity, and festinating gait (statements 1, 2, and 3) are all well-established signs suggestive of Parkinson's disease, while a positive Romberg test (statement 4) is not a feature of Parkinson's disease and instead points toward a sensory or vestibular deficit.

Hence, the correct answer is 1, 2 and 3.

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Important Questions from Neuropathies

  1. Consider the following clinical features : 

    1. Hypomimia 

    2. Dysphonia 

    3. Festination gait 

    4. Cogwheel rigidity 

    Which of the features given above are generally present in Parkinsonism?

  2. Circuits between the basal ganglia and the motor cortex constitute the extra pyramidal system which controls muscle tone, body posture and the initiation of movement. Lesions of the extra pyramidal system present clinically with :
  3. Consider the following statements regarding Transient Global Amnesia (TGA): 

    1. TGA mainly affects middle aged persons who present with abrupt, discrete loss of anterograde memory lasting for few hours. 

    2. During the episode, the patients are unable to record new memories resulting in repetitive questioning. 

    3. Consciousness is impaired during the episode and the patient is unable to perform even simple motor functions. 

    4. After 4-6 hours, memory function and behaviour return to normal but the patient has complete and persistent amnesia for the duration of the episode. 

    Which of the statements given above are correct?

  4. Which of the following correctly describes the primary position of the right eye in right 3rd cranial nerve palsy?
  5. Which one of the following distinguishes axonal degeneration from segmental demyelination on electrophysiological studies?
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