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Question

Which is the earliest sign of rickets?

The correct answer is

Craniotabes

Understanding the Earliest Signs of Rickets

Rickets is a condition that affects bone development in children. It is most commonly caused by a deficiency in vitamin D, calcium, or phosphate. These nutrients are crucial for building strong and healthy bones. When a child doesn't get enough of them, their bones can become soft and weak, leading to various deformities and symptoms.

Identifying Craniotabes as an Early Sign

Several signs can indicate rickets. However, some appear earlier than others, particularly in infants. Among the options provided:

  • Harrison's Groove: This is an indentation around the lower part of the chest, where the diaphragm attaches. It's a sign of weakened ribs pulling inward. It appears later in the disease process.
  • Craniotabes: This refers to softening of the skull bones, particularly the occipital and parietal bones. When pressure is applied, these areas may feel like pressing on a ping-pong ball or eggshell. Craniotabes is often the earliest detectable sign of rickets, especially in young infants (typically between 3 and 6 months of age).
  • Bow Legs: This is a deformity where the legs curve outwards at the knees. It occurs when the softened leg bones bend under the child's weight as they start standing and walking. This sign usually appears later, once the child is weight-bearing.
  • Rickety Rosary: This is a visible or palpable enlargement of the cartilage-bone junctions of the ribs, creating a bead-like appearance along the chest. Like Harrison's Groove, it is a sign related to the ribs and typically develops after Craniotabes.

Considering the typical progression of rickets, Craniotabes, the softening of the skull bones, is generally recognized as the earliest clinical sign, especially in infants before they begin weight-bearing. Other signs like Harrison's Groove, Bow Legs, and Rickety Rosary develop as the condition progresses and affects other parts of the skeleton that are under more stress or load.

Conclusion on Rickets Symptoms

While rickets presents with multiple signs affecting different parts of the skeleton, the softening of the skull known as Craniotabes is often the first manifestation observed in young infants suffering from the condition.

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Important Questions from Microbiology & Nutrition

  1. Deficiency of which vitamin causes defective bone mineralization disorder called rickets?

  2. Blood clotting time is considerably prolonged in deficiency of:

  3. Which of this increases absorption of iron except

  4. What is the temperature used for Autoclaving?

  5. Which is a macromineral that the body needs to work properly?

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