What ECG change might be seen after administration of calcium channel blockers?
Bradycardia
Non-dihydropyridine calcium channel blockers (verapamil, diltiazem) slow conduction through the SA and AV nodes by inhibiting slow L-type calcium currents. The typical ECG effect is sinus bradycardia and PR prolongation.
They do not cause sinus tachycardia or ventricular fibrillation, and they tend to narrow — not widen — the QRS by not affecting His-Purkinje sodium channels.
Hence, Bradycardia.
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Important Questions from Pharmacology
During ECG monitoring, which drug is most likely to cause bradycardia?
During high-dose vasopressor therapy, which ECG change most reliably indicates supply–demand ischemia due to increased afterload?
Which type of stress test involves the use of medication instead of physical exercise?
Which ECG change most reliably indicates quinidine toxicity?
What is the most appropriate initial management for a patient presenting with symptomatic bradyarrhythmia?
