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Question

The best cure rates for keloids are achieved by:

The correct answer is
Intralesional excision followed by radiotherapy

Effective Keloid Treatment Strategies

Achieving the highest cure rates for keloids typically involves a combination therapy approach that addresses both the bulk of the lesion and minimizes the risk of recurrence.

Comparing Keloid Treatment Modalities

Different treatments target keloids in various ways, impacting their effectiveness:

  • Surgical excision: While removing the keloid tissue, this method alone has a significant risk of recurrence, sometimes resulting in even larger keloids.
  • Localised irradiation: This can be used, often post-surgery, but its standalone effectiveness for high cure rates is limited and carries potential side effects.
  • Intralesional injection of triamcinolone: Corticosteroid injections are effective for flattening and reducing symptoms like itching but are generally not curative on their own.
  • Intralesional excision followed by radiotherapy: Combining the physical removal of the keloid with post-operative radiation therapy is recognized as a highly effective strategy. The radiotherapy helps to suppress cellular activity that can lead to regrowth, thereby significantly improving the long-term cure rates and reducing recurrence compared to excision alone or other single-modality treatments.

Therefore, the combination of surgical removal and subsequent radiotherapy offers the best prospect for achieving high cure rates in keloid management.

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Important Questions from Wounds

  1. Which of the following are risk factors for wound infection? 

    1. Malnutrition 

    2. Poor perfusion 

    3. Antibodies 

    4. Foreign body material 

    Select the correct answer using the code given below.

  2. Which of the following are types of wound healing? 

    1. Primary Intention 

    2. Secondary Intention 

    3. Tertiary Intention 

    4. Quaternary Intention 

    Select the correct answer using the code given below :

  3. Untidy wounds are characterised by which of the following ? 

    1. Crushed or avulsed tissues 

    2. Contamination wound 

    3. Devitalised tissue 

    4. No loss of tissue 

    Select the correct answer using the code given below :

  4. Which of the following are types of wound healing?
    1. Primary Intention
    2. Secondary Intention
    3. Tertiary Intention
    4. Quaternary Intention
    Select the correct answer using the code given below :

  5. Untidy wounds are characterised by which of the following?
    1. Crushed or avulsed tissues
    2. Contamination wound
    3. Devitalised tissue
    4. No loss of tissue
    Select the correct answer using the code given below :
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