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Question

The basic unit of nucleic acid is

The correct answer is

nucleotide

Nucleic Acid Basic Unit: Understanding the Building Blocks

Nucleic acids are essential macromolecules in biology, primarily known for storing and transmitting genetic information. The two main types are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Like other polymers such as proteins (made of amino acids) or polysaccharides (made of monosaccharides), nucleic acids are also made up of repeating smaller units.

The question asks for the basic unit of nucleic acid. Let's look at the options provided.

What is a Nucleotide?

A nucleotide is the fundamental building block of nucleic acids. Each nucleotide is composed of three parts:

  • A phosphate group
  • A pentose sugar (deoxyribose in DNA, ribose in RNA)
  • A nitrogenous base (Adenine, Guanine, Cytosine, Thymine in DNA; Adenine, Guanine, Cytosine, Uracil in RNA)

These nucleotides link together through phosphodiester bonds between the phosphate group of one nucleotide and the sugar of the next, forming the long chains of DNA and RNA.

What is a Nucleoside?

A nucleoside is similar to a nucleotide but lacks the phosphate group. It consists only of:

  • A pentose sugar (deoxyribose or ribose)
  • A nitrogenous base (Adenine, Guanine, Cytosine, Thymine, or Uracil)

Therefore, a nucleoside is a part of a nucleotide but not the complete repeating unit that forms the nucleic acid polymer.

What is a Nucleoid?

The nucleoid is a region within prokaryotic cells (like bacteria) where the genetic material, typically a circular DNA molecule, is located. It is not a molecule or a building block, but rather a cellular structure or region.

Comparing Nucleotide and Nucleoside

Here is a simple comparison of the components:

Component Nucleotide Nucleoside
Phosphate group Present Absent
Pentose sugar Present Present
Nitrogenous base Present Present

Conclusion: Identifying the Basic Unit of Nucleic Acid

Since nucleotides are the units that link together via phosphodiester bonds to form the polymer chain of DNA or RNA, they are considered the basic repeating unit or monomer of nucleic acids.

Based on the composition and how the nucleic acid chain is assembled, the nucleotide is the correct basic unit.

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Important Questions from Biochemistry

  1. Lactose is the substrate for which of the following enzyme ?

  2. Chemical name of Vitamin E is _________.

  3. The following table lists names of scientists and advances made by them

    Column AColumn B
    ALinus Pauling(i)Myoglobin structure
    BEmil Fischer(ii)Model of α-helix
    CJohn Kendrew(iii)Lock and Key model
    DChristian Anfinsen(iv)Sequence-structure

    Which one of the following options correctly matches contents of column A with column B?
  4. One gram of a polysaccharide composed of 1000 glucose units has the same effect on osmolarity as that of

  5. Several proteins are modified by phosphorylation at specific amino acid residues to alter their activities. Which one of the following amino acids is NOT typically a site of phosphorylation in proteins?

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