Growth Hormone Over-secretion Effects in Adults

The question asks about the condition resulting from the over-secretion of growth hormone specifically in adults.

Understanding Growth Hormone Over-secretion

Growth hormone (GH), produced by the pituitary gland, regulates growth and metabolism. When there is an excess secretion of GH after the natural growth period in adults (when the bone growth plates have closed), it leads to distinct physical changes.

Identifying the Correct Condition

• Acromegaly: This condition directly results from GH over-secretion in adults. It causes the gradual enlargement of bones, particularly in the hands, feet, and face, as well as increased growth of soft tissues.

Evaluating Incorrect Options

• Dwarfism: This is typically caused by a deficiency (under-secretion) of growth hormone during childhood and adolescence, leading to stunted growth.
• Addison's disease: This is a disorder of the adrenal glands, unrelated to growth hormone over-secretion. It involves insufficient production of certain hormones like cortisol.
• Graves' disease: This is an autoimmune disorder affecting the thyroid gland, leading to hyperthyroidism (overactive thyroid). It is not related to growth hormone levels.

Based on the effects of growth hormone over-secretion in adults, Acromegaly is the correct diagnosis.