Question
Nebulized salbutamol is used in the management of which of the following electrolyte abnormality?
The correct answer is
Hyperkalemia
Salbutamol Mechanism in Hyperkalemia
Nebulized salbutamol is primarily used to manage hyperkalemia, a condition characterized by elevated serum potassium levels.
Its mechanism involves the activation of beta-2 adrenergic receptors, which stimulates the sodium-potassium ATPase (Na+/K+-ATPase) pump located on cell membranes. This stimulation enhances the movement of potassium ions (K+) from the extracellular fluid into the intracellular fluid.
- Action: Beta-2 agonism stimulates the Na+/K+-ATPase pump.
- Effect: Facilitates intracellular shift of potassium (K+).
- Result: Decreases serum potassium concentration.
This acute reduction in serum K+ makes salbutamol a valuable tool in the emergency management of hyperkalemia.
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Important Questions from Electrolyte Imbalance
- Which of the following does NOT cause prolongation of QT interval?
- Which of the following does NOT causes polyuria?
- A 36-year old chronic alcoholic, malnourished male is hospitalized with pneumonia. His condition worsens after aggressive treatment with intravenous dextrose and antibiotics. This phenomenon of 'Refeeding Syndrome' is accompanied by which one of the following biochemical alterations?
- Which one of the following drugs causes hypercalcemia?
- Syndrome of Inappropriate ADH secretion (SIADH) is usually associated with:
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