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Question

Muscle contraction is initiated by a signal sent by the central nervous system by the release of ______

This question was previously asked in
NEET UG Re-Exam 2026 Question Paper (21-Jun-2026)
The correct answer is
acetyl choline

Muscle Contraction Signal from CNS

Muscle contraction is a complex process initiated by nerve impulses originating from the central nervous system (CNS). These impulses travel along motor neurons to the muscle.

Neuromuscular Junction Transmission

At the junction between a motor neuron and a muscle fiber, called the neuromuscular junction, the nerve impulse triggers the release of a specific chemical messenger. This messenger diffuses across the synaptic cleft and binds to receptors on the muscle cell membrane.

  • The binding process initiates an electrical signal in the muscle fiber.
  • This electrical signal leads to the release of calcium ions within the muscle cell.
  • The increased calcium concentration ultimately causes the muscle proteins to slide past each other, resulting in contraction.

Neurotransmitter Role

The primary neurotransmitter responsible for initiating this signal transmission at the neuromuscular junction is acetylcholine. The CNS releases acetylcholine to signal the muscle to contract.

Conclusion

Therefore, the signal released by the central nervous system to initiate muscle contraction is acetyl choline.

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Important Questions from Human Anatomy and Physiology-I

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