Match List I with List II List I List II Metalloprotein Metal A. carboxypeptidase A I. Mn B. oxygen-evolving complex II. Fe C. hemerythrin III. Ni D. coenzyme F-430 IV. Zn Choose the correct answer from the options given below:
A - IV, B - I, C - II, D - III
Metalloprotein and Metal Matching
Metalloproteins are proteins that contain a metal ion cofactor or prosthetic group, which is essential for their biological function. The question asks to match specific metalloproteins with the metal ions they contain.
Let's examine each metalloprotein listed and identify its characteristic metal cofactor:
- Carboxypeptidase A: This enzyme is a protease that requires a metal ion for its activity. It is a well-known zinc metalloenzyme. Therefore, Carboxypeptidase A contains Zinc (Zn). This matches with List II option IV.
- Oxygen-evolving complex: This complex is part of Photosystem II in plants and cyanobacteria and is responsible for splitting water molecules during photosynthesis, releasing oxygen. It is a manganese-containing complex. Therefore, the Oxygen-evolving complex contains Manganese (Mn). This matches with List II option I.
- Hemerythrin: This is an oxygen-binding protein found in marine invertebrates. Unlike hemoglobin or myoglobin, it contains iron directly bound to protein side chains, not in a porphyrin ring. It contains di-iron centers. Therefore, Hemerythrin contains Iron (Fe). This matches with List II option II.
- Coenzyme F-430: This is a nickel-containing tetrapyrrole (a type of porphyrin) which acts as a cofactor in the enzyme methyl coenzyme M reductase. This enzyme is crucial for the final step of methanogenesis in archaea. Therefore, Coenzyme F-430 contains Nickel (Ni). This matches with List II option III.
Based on this analysis, we can establish the following matches:
| List I (Metalloprotein) | List II (Metal) | Match |
|---|---|---|
| A. Carboxypeptidase A | I. Mn | A → IV. Zn |
| B. Oxygen-evolving complex | II. Fe | B → I. Mn |
| C. Hemerythrin | III. Ni | C → II. Fe |
| D. Coenzyme F-430 | IV. Zn | D → III. Ni |
The correct matching is A - IV, B - I, C - II, D - III.
Important Questions from Bioinorganic Chemistry
Consider the following transformation reactions in the context of co - enzyme B12
A. 1, 2 - Carbon shift
B. Hydration of CO2
C. Benzene to phenol
D. Dimethyl sulfide to dimethyl sulfoxide
The correct statement(s) for co - enzyme B12 is / are
During the binding of O2 to myoglobin (consider 'heme' in xy-plane), the molecular orbital of O2 and atomic orbital of Fe involved in the formation of the σ-bond is
In the catalytic cycle of Cytochrome P450, the generation of [(porphyrin)+•FeIV(O)] from [(porphyrin)FeIII(OOH)] involves
In solution, Vaska's complex is known to bind O2 reversibly. In the product, oxidation state of the metal ion center coordination geometry and mode of binding of O2, respectively are
The number of moles of Mg–ATP needed for the reduction of one mole of nitrogen by the nitrogenase enzyme is
