Question
Match List-I with List-IIList-1 List-II Drugs Routes of drug administration (A). Dopamine (I). Intradermal (B). Nitroglycerine (II). Intravenous (C). BCG vaccine (III). Subcutaneous (D). Insulin (IV). Sublingual
Choose the correct answer from the options given below:
The correct answer is
(A) - (II), (B) - (IV), (C) - (I), (D) - (III)
Matching Drugs to Routes of Administration: MCQ Solution
This question involves matching specific pharmaceutical drugs with their correct routes of administration. This is a fundamental concept in medicine, ensuring drugs are delivered effectively and safely.
Understanding Drug Administration Routes
Different ways of giving medicines (routes) are chosen based on what the medicine is supposed to do, how quickly it needs to work, and how long its effect should last. Here are the routes mentioned:
- Intravenous (IV): Given directly into a vein. This method leads to the fastest absorption as the drug enters the bloodstream immediately.
- Sublingual: Placed under the tongue. The medicine dissolves and is absorbed quickly through the lining of the mouth, bypassing the stomach and liver initially.
- Intradermal: Given just under the top layer of skin (the dermis). Absorption is very slow, often used for allergy testing or specific vaccines.
- Subcutaneous: Given into the fatty tissue layer just below the skin. Absorption is slower than IV or intramuscular routes, providing a more gradual effect.
Drug-Route Pairings Analysis
Let's examine each drug from List-I and pair it with its most suitable route from List-II:
- (A) Dopamine: This drug is a powerful medication used to treat low blood pressure and shock, often in emergency situations. It needs to enter the bloodstream quickly and its dosage must be precisely controlled. Therefore, the Intravenous (II) route is essential.
- (B) Nitroglycerine: This medication is commonly used to relieve chest pain (angina). When given as a tablet or spray under the tongue (Sublingual (IV)), it gets absorbed rapidly into the bloodstream, providing fast relief.
- (C) BCG vaccine: This vaccine helps protect against tuberculosis. The standard method for administering the BCG vaccine is an Intradermal (I) injection, meaning it's given very superficially into the skin.
- (D) Insulin: Used by people with diabetes to control blood sugar levels. Insulin is typically injected into the layer of fat just beneath the skin (Subcutaneous (III)). This route allows the insulin to be absorbed slowly over time, helping to manage blood glucose levels steadily.
Matching Summary Table
| Drug (List-I) | Route of Administration (List-II) | Reason for Route Choice |
|---|---|---|
| (A) Dopamine | (II) Intravenous | Allows for rapid onset and precise dose titration in critical care. |
| (B) Nitroglycerine | (IV) Sublingual | Enables quick absorption for rapid relief of angina symptoms. |
| (C) BCG vaccine | (I) Intradermal | Standard administration for eliciting a localized immune response. |
| (D) Insulin | (III) Subcutaneous | Provides slow and sustained absorption for effective blood glucose control. |
Final Correct Drug-Route Identification
Based on the analysis, the correct pairings are:
- (A) Dopamine corresponds to (II) Intravenous.
- (B) Nitroglycerine corresponds to (IV) Sublingual.
- (C) BCG vaccine corresponds to (I) Intradermal.
- (D) Insulin corresponds to (III) Subcutaneous.
This set of matches accurately reflects standard medical practices for administering these drugs.
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Important Questions from Miscellaneous
- Which of the following relationships is/are not true?
(A). Most probable velocity = $\sqrt{\frac{2RT}{M}}$
(B). PV = $\frac{3}{2}kT$
(C). Compressibility factor Z = $\frac{pV}{nRT}$
(D). Average kinetic energy of gas = $\frac{1}{2}kT$
Choose the correct answer from the options given below - Match List-I with List-II
List-I List-II Electronic Configuration First Ionisation energy (kJ mol$^{-1}$) (A). ns$^2$ (I). 2100 (B). ns$^2$np$^1$ (II). 1400 (C). ns$^2$np$^3$ (III). 800 (D). ns$^2$np$^6$ (IV). 900
Choose the correct answer from the options given below: - The shielding constant of a 2p electron (calculated using Slater's rules) is
- Match List-I with List-II
List-I List-II Spectroscopy Property (A). Raman (I). Polarizability (B). FTIR (II). Dipole Moment (C). UV-Visible (III). Absorbance (D). NMR (IV). Spin
Choose the correct answer from the options given below: - The structure of protein comprises of:
(A). Primary structure of protein is associated with amino acids
(B). Secondary structure of protein is associated to peptides
(C). Tertiary structure of protein is associated with polypeptide chains
(D). Quaternary structure of protein is associated with polypeptide chains
Choose the correct answer from the options given below:
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