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Question

Match List I with List II and select the correct answer using the Code given below the lists:
 

 List I (Antidote) List II (Poison/Drug)
ACalcium sodium edetate1Cyanide
BSodium nitrite2Nitrobenzene
CMethylene blue3 Lead
DAtropine4Organophosphate
  5Kerosene

The correct answer is

A-3, B-1, C-2, D-4 

Antidote Poison Matching Explained 

This question requires matching specific antidotes from List I to their corresponding poisons or drugs listed in List II. Understanding these pairings is crucial for toxicology and emergency medicine.

Key Antidote-Poison Pairings

Based on the provided correct answer, the established pairings are:

  • Calcium sodium edetate (A) is correctly matched with Lead (3). This antidote acts as a chelating agent, binding to lead ions to facilitate their excretion from the body, treating lead poisoning.
  • Sodium nitrite (B) is correctly matched with Cyanide (1). It is used to treat cyanide poisoning by oxidizing hemoglobin to methemoglobin, which binds cyanide more effectively than hemoglobin.
  • Methylene blue (C) is correctly matched with Nitrobenzene (2). Methylene blue is the primary antidote for methemoglobinemia, a condition induced by substances like nitrobenzene where hemoglobin's oxygen-carrying capacity is reduced.
  • Atropine (D) is correctly matched with Organophosphate (4). Atropine is a vital medication used to counteract the dangerous overstimulation of the parasympathetic nervous system caused by organophosphates.

Summary of Correct Matches

The correct matching of List I (Antidote) to List II (Poison/Drug) is summarized below:

Antidote (List I)Poison/Drug (List II)Match Number
A: Calcium sodium edetateLead3
B: Sodium nitriteCyanide1
C: Methylene blueNitrobenzene2
D: AtropineOrganophosphate4

This corresponds to option 4, where A=3, B=1, C=2, and D=4.

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Important Questions from Acute Poisoning

  1. Which of the following toxidromes is associated with the consumption of pesticides containing organophosphates?

  2. Which of the following is the primary antidote used in children with organophosphate poisoning?

  3. Which one of the following drugs is the antidote for benzodiazepine poisoning?
  4. A 3-year old child develops severe respiratory distress after inhalation of fumes arising from burning plastic. The child is started on supportive ventilation. Which one of the following antidotes needs to be given?

  5. All of the following features are present in Organophosphorus poisoning EXCEPT:
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