Question
Match List-I with List-II and select the correct answer using the code given below the lists : List-I (disease state) List-II (clinical feature) A Pemphigus vulgaris 1 Acro –osteolysis B Psoriasis 2 Brachydactyly C Turner syndrome 3 Koebner phenomenon D Primary hyperparathyroidism 4 Nikolsky sign
The correct answer is
A-4, B-3, C-2, D-1
Matching Disease States with Clinical Features
This question involves matching specific disease states from List-I with their corresponding clinical features presented in List-II.
Disease-Feature Matching Explained
- A. Pemphigus vulgaris: This is an autoimmune condition causing skin blistering. The characteristic clinical sign is the Nikolsky sign (4), where skin easily separates or blisters upon slight friction.
- B. Psoriasis: A common chronic skin disease. A notable feature is the Koebner phenomenon (3), where new skin lesions develop at sites of injury or trauma.
- C. Turner syndrome: This genetic disorder affects females. Brachydactyly (2), characterized by abnormally short fingers and toes, is a frequent skeletal finding.
- D. Primary hyperparathyroidism: This condition results from overactive parathyroid glands. A significant skeletal consequence is Acro-osteolysis (1), which involves bone resorption, particularly in the terminal phalanges.
Correct Matching Code Selection
Based on the distinct clinical features associated with each disease:
- Pemphigus vulgaris (A) matches Nikolsky sign (4).
- Psoriasis (B) matches Koebner phenomenon (3).
- Turner syndrome (C) matches Brachydactyly (2).
- Primary hyperparathyroidism (D) matches Acro-osteolysis (1).
Therefore, the correct code is A-4, B-3, C-2, D-1.
| A | B | C | D |
| 4 | 3 | 2 | 1 |
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