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Question

Koebner phenomenon is seen in which one of the following conditions?

The correct answer is
Psoriasis

Understanding the Koebner Phenomenon

The Koebner phenomenon, also known as the isomorphic response, is a specific dermatological finding where new skin lesions appear in areas of the body that have experienced trauma or injury.

This phenomenon is observed in several skin conditions. The trauma can include scratches, cuts, burns, or even pressure on the skin. The new lesions that develop typically resemble the primary disease.

Identifying Koebner Phenomenon in Psoriasis

Psoriasis is a chronic autoimmune disease that primarily affects the skin. It is well-known for exhibiting the Koebner phenomenon.

In individuals with psoriasis, minor injuries to the skin, such as those caused by scratching an itch, shaving, or insect bites, can trigger the development of new psoriatic plaques in the traumatized areas, usually within a few days to weeks.

This characteristic response makes Psoriasis a prime example of a condition where the Koebner phenomenon is frequently observed.

Analyzing Other Conditions and Koebner Phenomenon

Let's look at why the other options are less associated with the Koebner phenomenon compared to Psoriasis:

  • Acne Vulgaris: While inflammation and scarring can occur in acne, the Koebner phenomenon is not a typical feature. Acne lesions develop due to factors like clogged pores, bacteria, and inflammation, not primarily in response to skin trauma in a patterned way.
  • Bechet's disease: This is a systemic vasculitis characterized by ulcers in the mouth, on the genitals, and inflammatory eye conditions. While skin lesions can occur, the Koebner phenomenon is not a defining or common characteristic of Bechet's disease.
  • Leprosy: Leprosy is an infectious disease caused by Mycobacterium leprae. While skin manifestations are prominent, the Koebner phenomenon is not considered a hallmark characteristic of leprosy in the way it is for psoriasis.

Summary of Koebner Phenomenon Association

The Koebner phenomenon highlights how certain skin diseases can manifest traumatically induced lesions. Among the given options, Psoriasis is the condition most notably associated with this response.

Condition Association with Koebner Phenomenon
Psoriasis Strongly associated; characteristic finding
Acne Vulgaris Not typically associated
Bechet's disease Not typically associated
Leprosy Not a primary characteristic

Conclusion

Based on the understanding of the Koebner phenomenon and its prevalence in various dermatological conditions, Psoriasis is the condition where this response is most commonly observed.

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Important Questions from Miscellaneous

  1. A 35 year old male presents with increased urine output. On evaluation, his urinary output was around 4L/day; urinary osmolality was 200 mosmol/L. Which of the following are various differential diagnosis ?

    I. Psychogenic polydipsia

    II. Solute diuresis

    III. Central diabetes insipidus

    IV. Nephrogenic diabetes insipidus

    Select the correct answer using the
    code given below:

  2. Which one of the following causes low-volume erythrocytosis?

  3. Under which one of the following conditions, the HPA axis suppression is likely to result in crisis due to adrenal insufficiency following withdrawal of glucocorticoids?

  4. A 36 year old man presents with decreased apetite, mouth soreness, diarrhoea and irritability. On examination he has a bright red tongue with a pigmented scaly rash around the neck. Which one of the following food items in his diet has a bearing on his disease?

  5. Consider the following regarding the human hair growth cycle:

    I. Anagen is a phase of active hair growth

    II. Telogen is a transitional phase

    III. Catagen is a resting phase

    Which of the statements given above is/are correct?

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