All Exams Test series for 1 year @ ₹349 only
Question

In a town, a study was carried out to determine the role of cigarette smoking in causation of lung cancer. It was found that a total of 7000 people in the town were smokers. Of them, 70 developed lung cancer. In the same town, 3000 people were non-smokers. Of them, 3 developed lung cancer. Given these numbers, what would be the attributable risk to cigarette smoking for lung cancer?

The correct answer is

30%

Concept: Attributable Risk (Attributable Risk Percent)

Attributable Risk (AR) is the amount of disease incidence that can be directly attributed to a specific exposure — here, cigarette smoking. It is calculated as the difference between the incidence rate of disease in the exposed group and the incidence rate in the unexposed group, expressed as a percentage of the incidence in the exposed group.

Step 1: Incidence in Smokers (Exposed Group)

  • Total smokers = 7,000
  • Developed lung cancer = 70
  • Incidence in smokers (Ie) = 70 / 7,000 = 0.01 = 1% (10 per 1,000)

Step 2: Incidence in Non-Smokers (Unexposed Group)

  • Total non-smokers = 3,000
  • Developed lung cancer = 3
  • Incidence in non-smokers (Iu) = 3 / 3,000 = 0.001 = 0.1% (1 per 1,000)

Step 3: Calculating Attributable Risk Percent

$$\text{AR\%} = \frac{I_e - I_u}{I_e} \times 100$$

$$\text{AR\%} = \frac{0.01 - 0.001}{0.01} \times 100 = \frac{0.009}{0.01} \times 100 = 90\%$$

This means that 90% of the lung cancer risk among smokers is directly attributable to cigarette smoking, while the remaining 10% of the risk would exist even without smoking (background/baseline risk).

Why the Other Options Are Incorrect

  • 10% — This is actually the proportion of risk in smokers that is not attributable to smoking (Iu/Ie × 100 = 0.1/1 × 100 = 10%); it is the inverse of the correct answer, not the attributable risk itself.
  • 30% — Does not correspond to any standard attributable risk calculation using the given incidence values; there is no valid epidemiological formula applied to these numbers (Ie = 1%, Iu = 0.1%) that yields 30%.
  • 60% — Also does not match any recognized attributable risk, relative risk, or population attributable risk formula for this dataset.

Key Takeaway

Given Ie = 1% and Iu = 0.1%, the correctly computed Attributable Risk Percent = 90%, making it the mathematically and epidemiologically correct answer for this classic study design comparing smokers and non-smokers.

Was this answer helpful?

Important Questions from General Epidemiology

  1. Poor hand hygiene of a mess worker in a university college mess led to Hepatitis A cases in the hostel inmates. What type of epidemic will this exposure present with?
    1. Propagated
    2. Common source-continuous exposure
    3. Common source-point exposure
    Select the correct answer using the code given below:

  2. Which one of the following is NOT a function of Epidemiology?
  3. Predictive accuracy of a screening test depends on the following EXCEPT:
  4. Which one of the following statements is NOT true for taking a decision on screening for disease?

  5. Standardized Mortality ratio is best explained by which one of the following statements?
Need Expert Advice?

Start Your Preparation with Prepp Mobile App

Download the app from Google Play & App Store
Download the app from Google Play & App Store
Prepp Mobile App