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Question

In a patient of primary hypothyroidism, the hormonal profile will read

The correct answer is
Low $T_3$, low $T_4$, normal TSH

Primary Hypothyroidism Hormonal Profile

Primary hypothyroidism occurs when the thyroid gland itself fails to produce adequate thyroid hormones ($T_3$ and $T_4$).

Hormonal Profile Analysis

In a patient diagnosed with primary hypothyroidism, the characteristic hormonal profile typically shows:

  • Thyroid Hormones ($T_3$ and $T_4$): Levels are low. This indicates the thyroid gland is underactive and not producing sufficient amounts of these essential hormones.
  • Thyroid-Stimulating Hormone (TSH): The level is normal.

Therefore, the hormonal profile reads low $T_3$, low $T_4$, and normal TSH.

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Important Questions from Thyroid Disorders

  1. Which one of the following diseases is characterized by destructive lymphoid infiltration of the thyroid gland leading to fibrosis and enlargement of the thyroid gland with an increased risk of developing thyroid lymphoma?
  2. With regards to treatment of thyrotoxicosis of Grave's disease, consider the following statements: 

    1. Propylthiouracil is suitable in breastfeeding patients. 

    2. Large goitre is an indication for thyroidectomy. 

    3. Radioiodine is recommended for management in pregnancy. 

    4. Agranulocytosis is a complication associated with carbimazole. 

    Which of the statements given above are correct?

  3. With regard to management of hypothyroidism, consider the following statements: 

    1. Treatment is with levothyroxine replacement. 

    2. It is taken as a single daily dose. 

    3. Average dose is 1.6 $\mu$gm/kg/day. 

    4. Full dose per weight should be started in those with coronary artery disease. 

    Which of the statements given above are correct?

  4. Low serum thyroglobulin levels are seen in
  5. A 27-year lady underwent thyroidectomy for thyroid carcinoma. Post-operatively she started developing muscle cramps, perioral and peripheral paresthesia, and carpopedal spasm. Which one of the following interventions will be appropriate for this patient?
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