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Question

Erythrocyte glutathione reductase (EGR) activation test is the most accepted procedure for assessing the status of :

The correct answer is
Riboflavin

EGR Activation Test Purpose

The Erythrocyte glutathione reductase (EGR) activation test is a specific biochemical assay used to evaluate the nutritional status of a particular vitamin.

Assessing Riboflavin Status

This test measures the activity of the enzyme glutathione reductase found in red blood cells (erythrocytes). The activity of this enzyme is dependent on its coenzyme form, Flavin Adenine Dinucleotide (FAD).

  • FAD is synthesized in the body from Riboflavin (Vitamin B2).
  • A deficiency in Riboflavin leads to lower levels of FAD.
  • Consequently, this reduces the activity of the EGR enzyme.
  • The EGR activation test quantifies the enzyme's activity with and without added FAD. The degree of activation directly correlates with the body's Riboflavin status.

Therefore, the Erythrocyte glutathione reductase (EGR) activation test is the accepted method for assessing the nutritional status of Riboflavin.

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    List-II
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